GATA4 and MDC1

  • Number of citations of the paper that reports this interaction (PubMedID 14578343)
  • 91
  • Data Source:
  • BioGRID (unspecified method)

GATA4

MDC1

Description GATA binding protein 4 mediator of DNA damage checkpoint 1
Image
GO Annotations Cellular Component
Molecular Function
Biological Process
Pathways
Drugs
Diseases
GWAS
  • Adventurousness ( 30643258)
  • Atrial fibrillation ( 30061737 29892015)
  • Body shape index ( 34021172)
  • Brain morphology (MOSTest) ( 32665545)
  • Diastolic blood pressure ( 27618452)
  • Diastolic blood pressure (cigarette smoking interaction) ( 29455858)
  • Fish- and plant-related diet ( 32066663)
  • Fruit consumption ( 32066663)
  • General factor of neuroticism ( 30867560)
  • General risk tolerance (MTAG) ( 30643258)
  • Left ventricular global circumferential strain (MTAG) ( 33495596)
  • Left ventricular global longitudinal strain (MTAG) ( 33495596)
  • Medication use (agents acting on the renin-angiotensin system) ( 31015401)
  • Medication use (diuretics) ( 31015401)
  • Myopia (pathological) ( 23049088)
  • Polycystic ovary syndrome ( 26284813)
  • Processed meat consumption ( 32066663)
  • Refractive error ( 32231278)
  • Retinal vascular caliber ( 21060863)
  • Systolic blood pressure ( 28135244 28739976 27618452)
  • Systolic blood pressure (cigarette smoking interaction) ( 29455858)
  • Systolic blood pressure x alcohol consumption interaction (2df test) ( 29912962)
  • Testicular germ cell tumor ( 28604728)
  • Triglyceride levels ( 32203549)
  • Waist circumference adjusted for body mass index ( 34021172)
  • Waist-hip index ( 34021172)
  • Waist-to-hip ratio adjusted for BMI ( 34021172)
Interacting Genes 24 interacting genes: ALX4 CRIP2 EP300 FOS HAND2 ID1 ID2 ID3 JARID2 MAPK1 MAPK3 MDC1 MED1 MEF2C NFATC4 NKX2-5 NR5A1 PIAS1 RACK1 SP1 SRF TBX5 ZBTB3 ZFPM2 41 interacting genes: ANAPC1 ATM BARD1 BDKRB1 BRCA1 CASP3 CENPC CHEK2 COPS5 CREBBP CSNK2A1 DTX2 EP300 GATA4 H2AX HDAC10 HDAC8 HINFP NBN NCL NSD2 PIAS1 PIAS4 PRIM1 PTEN RAD50 RAD51 RNF8 SMC1A SRPK2 SUMO2 TNKS2 TP53 TP53BP1 UIMC1 USP13 USP15 USP28 VAMP5 WRN ZNF251
Entrez ID 2626 9656
HPRD ID 08994 16252
Ensembl ID ENSG00000136574 ENSG00000137337
Uniprot IDs B3KUF4 B6DU75 P43694 A0A1U9XBC1 A1Z5I9 Q14676
PDB IDs 2M9W 2ADO 2AZM 2ETX 3K05 3UEO 3UMZ 3UN0 3UNM 3UNN 3UOT
Enriched GO Terms of Interacting Partners?
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