IRF2BP1 and PCBD2

Number of citations of the paper that reports this interaction (PubMedID 20211142)
361

Data Source:
BioGRID (two hybrid)

		IRF2BP1	PCBD2
Description		interferon regulatory factor 2 binding protein 1	pterin-4 alpha-carbinolamine dehydratase 2
Image		No pdb structure
GO Annotations	Cellular Component	Nucleus Nucleoplasm	Cellular_component Nucleus
	Molecular Function	Transcription Corepressor Activity Protein Binding Metal Ion Binding Ubiquitin Protein Ligase Activity	Phenylalanine 4-monooxygenase Activity Protein Binding 4-alpha-hydroxytetrahydrobiopterin Dehydratase Activity Identical Protein Binding
	Biological Process	Negative Regulation Of Transcription By RNA Polymerase II Protein Polyubiquitination Regulation Of Transcription By RNA Polymerase II	Tetrahydrobiopterin Biosynthetic Process Tyrosine Biosynthetic Process, By Oxidation Of Phenylalanine Positive Regulation Of Transcription, DNA-templated
Pathways
Drugs
Diseases
GWAS		Apolipoprotein A1 levels ( 32203549) Asthma ( 31959851) Gallstone disease ( 30504769) HDL cholesterol levels ( 32203549) Mean corpuscular hemoglobin ( 32888494)	Bulimia nervosa ( 23568457) Colorectal cancer ( 23263487) Height ( 28552196 18391951) Type 2 diabetes ( 24509480)
Interacting Genes		8 interacting genes: ATF2 IRF2 IRF9 JDP2 PCBD2 SMAD1 TGIF1 UBE2L3	41 interacting genes: AATF APP ASCC2 BCAS2 BRF1 C1D CDC5L CENPK CERS3 CHAF1A F2RL1 FBXO7 GTF2E1 GUCD1 HES4 IRF2BP1 KCNIP3 KLC3 LGALS14 MAGEA11 MAGEA6 MED21 MED30 MED4 MED7 MET MRFAP1 PBXIP1 PCBD1 PHF14 PML RUNX1T1 SNW1 SPG21 SSX3 SSX5 STAT3 TAL2 TGIF2LY XBP1 ZZZ3
Entrez ID		26145	84105
HPRD ID		17159	17824
Ensembl ID		ENSG00000170604	ENSG00000132570
Uniprot IDs		Q8IU81	Q9H0N5
PDB IDs			4C45
Enriched GO Terms of Interacting Partners?
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