PCBD2 and C1D

Number of citations of the paper that reports this interaction (PubMedID 20211142)
361

Data Source:
BioGRID (two hybrid)

		PCBD2	C1D
Description		pterin-4 alpha-carbinolamine dehydratase 2	C1D nuclear receptor corepressor
Image			No pdb structure
GO Annotations	Cellular Component	Cellular_component Nucleus	Nuclear Exosome (RNase Complex) Exosome (RNase Complex) Nucleus Nucleoplasm Nucleolus Cytoplasm Transcription Repressor Complex
	Molecular Function	Phenylalanine 4-monooxygenase Activity Protein Binding 4-alpha-hydroxytetrahydrobiopterin Dehydratase Activity Identical Protein Binding	DNA Binding Transcription Corepressor Activity RNA Binding Protein Binding Nuclear Receptor Binding
	Biological Process	Tetrahydrobiopterin Biosynthetic Process Tyrosine Biosynthetic Process, By Oxidation Of Phenylalanine Positive Regulation Of Transcription, DNA-templated	Maturation Of 5.8S RRNA Apoptotic Process Regulation Of Gene Expression Negative Regulation Of Transcription, DNA-templated
Pathways			Major pathway of rRNA processing in the nucleolus and cytosol
Drugs
Diseases
GWAS		Bulimia nervosa ( 23568457) Colorectal cancer ( 23263487) Height ( 28552196 18391951) Type 2 diabetes ( 24509480)	Familial lung adenocarcinoma ( 29924316) Male-pattern baldness ( 27182965) Obstetric antiphospholipid syndrome ( 28424481) PR interval ( 32439900) Restless legs syndrome ( 29029846) Schizophrenia x sex interaction ( 34099189) Systolic blood pressure response to hydrochlorothiazide in hypertension ( 27802415)
Interacting Genes		41 interacting genes: AATF APP ASCC2 BCAS2 BRF1 C1D CDC5L CENPK CERS3 CHAF1A F2RL1 FBXO7 GTF2E1 GUCD1 HES4 IRF2BP1 KCNIP3 KLC3 LGALS14 MAGEA11 MAGEA6 MED21 MED30 MED4 MED7 MET MRFAP1 PBXIP1 PCBD1 PHF14 PML RUNX1T1 SNW1 SPG21 SSX3 SSX5 STAT3 TAL2 TGIF2LY XBP1 ZZZ3	16 interacting genes: APP GSC2 IL23R MOGS NCOR1 NCOR2 NR1D1 PCBD2 PRKDC SASH1 SH3GLB1 SUOX THRA THRB TSNAX ZGPAT
Entrez ID		84105	10438
HPRD ID		17824	07382
Ensembl ID		ENSG00000132570	ENSG00000197223
Uniprot IDs		Q9H0N5	Q13901
PDB IDs		4C45
Enriched GO Terms of Interacting Partners?
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