IRF2BP1 and JDP2

Number of citations of the paper that reports this interaction (PubMedID 18671972)
12

Data Source:
BioGRID (pull down)

		IRF2BP1	JDP2
Description		interferon regulatory factor 2 binding protein 1	Jun dimerization protein 2
Image		No pdb structure	No pdb structure
GO Annotations	Cellular Component	Nucleus Nucleoplasm	Chromatin Nucleus
	Molecular Function	Transcription Corepressor Activity Protein Binding Metal Ion Binding Ubiquitin Protein Ligase Activity	RNA Polymerase II Cis-regulatory Region Sequence-specific DNA Binding DNA-binding Transcription Factor Activity, RNA Polymerase II-specific DNA-binding Transcription Repressor Activity, RNA Polymerase II-specific Chromatin Binding Protein Binding Protein-containing Complex Binding Sequence-specific Double-stranded DNA Binding
	Biological Process	Negative Regulation Of Transcription By RNA Polymerase II Protein Polyubiquitination Regulation Of Transcription By RNA Polymerase II	Negative Regulation Of Transcription By RNA Polymerase II Regulation Of Transcription By RNA Polymerase II Positive Regulation Of Histone Deacetylation Negative Regulation Of Fat Cell Differentiation
Pathways
Drugs			Pseudoephedrine
Diseases
GWAS		Apolipoprotein A1 levels ( 32203549) Asthma ( 31959851) Gallstone disease ( 30504769) HDL cholesterol levels ( 32203549) Mean corpuscular hemoglobin ( 32888494)	Allergic disease (asthma, hay fever or eczema) ( 29083406) Basal cell carcinoma ( 31174203 33549134) Keratinocyte cancer (MTAG) ( 31174203) Multiple sclerosis ( 24076602) Obesity-related traits ( 23251661) Periodontal microbiota ( 22699663)
Interacting Genes		8 interacting genes: ATF2 IRF2 IRF9 JDP2 PCBD2 SMAD1 TGIF1 UBE2L3	23 interacting genes: ATF2 ATF4 CREB5 CREBBP DDIT3 EP300 GTF2H1 HDAC1 HDAC4 HDAC5 HDAC6 IRF2BP1 JUN JUNB JUND KAT2B MAPK14 MAPK8 MAPK9 NEK9 PGR SNW1 TP53
Entrez ID		26145	122953
HPRD ID		17159	16360
Ensembl ID		ENSG00000170604	ENSG00000140044
Uniprot IDs		Q8IU81	A0A024R6D7 Q8WYK2
PDB IDs
Enriched GO Terms of Interacting Partners?
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