PCBD2 and HES4

Number of citations of the paper that reports this interaction (PubMedID 20211142)
361

Data Source:
BioGRID (two hybrid)

		PCBD2	HES4
Description		pterin-4 alpha-carbinolamine dehydratase 2	hes family bHLH transcription factor 4
Image			No pdb structure
GO Annotations	Cellular Component	Cellular_component Nucleus	Chromatin Nucleus
	Molecular Function	Phenylalanine 4-monooxygenase Activity Protein Binding 4-alpha-hydroxytetrahydrobiopterin Dehydratase Activity Identical Protein Binding	RNA Polymerase II Cis-regulatory Region Sequence-specific DNA Binding DNA-binding Transcription Factor Activity, RNA Polymerase II-specific Protein Binding Protein Dimerization Activity
	Biological Process	Tetrahydrobiopterin Biosynthetic Process Tyrosine Biosynthetic Process, By Oxidation Of Phenylalanine Positive Regulation Of Transcription, DNA-templated	Regulation Of Transcription By RNA Polymerase II Nervous System Development Anterior/posterior Pattern Specification Cell Differentiation
Pathways
Drugs
Diseases
GWAS		Bulimia nervosa ( 23568457) Colorectal cancer ( 23263487) Height ( 28552196 18391951) Type 2 diabetes ( 24509480)	HDL cholesterol levels ( 32203549)
Interacting Genes		41 interacting genes: AATF APP ASCC2 BCAS2 BRF1 C1D CDC5L CENPK CERS3 CHAF1A F2RL1 FBXO7 GTF2E1 GUCD1 HES4 IRF2BP1 KCNIP3 KLC3 LGALS14 MAGEA11 MAGEA6 MED21 MED30 MED4 MED7 MET MRFAP1 PBXIP1 PCBD1 PHF14 PML RUNX1T1 SNW1 SPG21 SSX3 SSX5 STAT3 TAL2 TGIF2LY XBP1 ZZZ3	5 interacting genes: COPG2 LTN1 PCBD1 PCBD2 RGS3
Entrez ID		84105	57801
HPRD ID		17824	16273
Ensembl ID		ENSG00000132570	ENSG00000188290
Uniprot IDs		Q9H0N5	D6REB3 E9PB28 Q9HCC6
PDB IDs		4C45
Enriched GO Terms of Interacting Partners?
Tagcloud ?
Tagcloud (Difference) ?
Tagcloud (Intersection) ?