RASGRP3 and DYNLL2

Number of citations of the paper that reports this interaction (PubMedID 25416956)
484

Data Source:
BioGRID (two hybrid)

		RASGRP3	DYNLL2
Description		RAS guanyl releasing protein 3	dynein light chain LC8-type 2
Image		No pdb structure
GO Annotations	Cellular Component	Plasma Membrane Integral Component Of Plasma Membrane Guanyl-nucleotide Exchange Factor Complex Perinuclear Region Of Cytoplasm	Nucleus Centrosome Cytosol Cytoplasmic Dynein Complex Microtubule Plasma Membrane Cilium Postsynaptic Density Membrane Dynein Complex Myosin V Complex Ciliary Tip 9+0 Non-motile Cilium Postsynapse Glutamatergic Synapse
	Molecular Function	Guanyl-nucleotide Exchange Factor Activity GTPase Activator Activity Calcium Ion Binding Protein Binding Kinase Binding Diacylglycerol Binding Small GTPase Binding	Protein Binding Identical Protein Binding Protein-containing Complex Binding Dynein Intermediate Chain Binding Dynein Light Intermediate Chain Binding Scaffold Protein Binding
	Biological Process	MAPK Cascade Small GTPase Mediated Signal Transduction Ras Protein Signal Transduction Regulation Of GTPase Activity	Microtubule-based Process Cilium Assembly
Pathways		Activation of RAS in B cells Activation of RAS in B cells RAF/MAP kinase cascade	Activation of BMF and translocation to mitochondria Amplification of signal from unattached kinetochores via a MAD2 inhibitory signal Macroautophagy MHC class II antigen presentation Separation of Sister Chromatids Resolution of Sister Chromatid Cohesion HSP90 chaperone cycle for steroid hormone receptors (SHR) in the presence of ligand Intraflagellar transport RHO GTPases Activate Formins COPI-mediated anterograde transport COPI-independent Golgi-to-ER retrograde traffic Mitotic Prometaphase HCMV Early Events Aggrephagy Aggrephagy EML4 and NUDC in mitotic spindle formation
Drugs
Diseases
GWAS		Albumin-globulin ratio ( 29403010) Bronchopulmonary dysplasia in preterm infants ( 30113228) Hypertension (young onset) ( 19421330) IgG response to Plasmodium falciparum antigens (GLURP, MSP2 FC27, MSP2 3D7) ( 26741287) Metabolite levels ( 23823483) Multiple system atrophy (pathologically confirmed) ( 27629089) Non-albumin protein levels ( 29403010) Non-response to antidepressants and depression ( 27622933) SjÃ¶gren's syndrome ( 24097067) Systemic lupus erythematosus ( 27399966 23273568 33272962 26663301 28714469 19838193)	Blood protein levels ( 30072576)
Interacting Genes		12 interacting genes: APP DYNC2LI1 DYNLL2 GET1 HSD17B11 PIK3CA PRKACA PRKCB PRKCD PRKCE PRKCQ SULT1C2	43 interacting genes: BCL2L11 BMF C12orf40 C14orf119 C17orf67 CHMP5 DLGAP1 DNAL4 DPPA3 DYNC1I1 EWSR1 F13A1 FAM117B GABARAPL2 GPHN GPRIN2 HDAC6 HMBOX1 HOMER3 HSF5 IHO1 KANK2 KIF2B MEOX2 MORN3 MSI2 MYO5A OTUD6A PAK1 PKIA PKIG PRKD3 RASGRP3 SECISBP2L SKAP1 SMCP SPAG8 STXBP4 THAP10 TLK1 TPPP XIAP ZAR1
Entrez ID		25780	140735
HPRD ID		15213	06489
Ensembl ID		ENSG00000152689	ENSG00000264364
Uniprot IDs		Q8IV61	Q96FJ2
PDB IDs			2XQQ 3P8M 4D07
Enriched GO Terms of Interacting Partners?
Tagcloud ?
Tagcloud (Difference) ?
Tagcloud (Intersection) ?