DYNLL2 and C17orf67

		DYNLL2	C17orf67
Description		dynein light chain LC8-type 2	chromosome 17 open reading frame 67
Image			No pdb structure
GO Annotations	Cellular Component	Nucleus Centrosome Cytosol Cytoplasmic Dynein Complex Microtubule Plasma Membrane Cilium Postsynaptic Density Membrane Dynein Complex Myosin V Complex Ciliary Tip 9+0 Non-motile Cilium Postsynapse Glutamatergic Synapse	Extracellular Region
	Molecular Function	Protein Binding Identical Protein Binding Protein-containing Complex Binding Dynein Intermediate Chain Binding Dynein Light Intermediate Chain Binding Scaffold Protein Binding	Protein Binding
	Biological Process	Microtubule-based Process Cilium Assembly
Pathways		Activation of BMF and translocation to mitochondria Amplification of signal from unattached kinetochores via a MAD2 inhibitory signal Macroautophagy MHC class II antigen presentation Separation of Sister Chromatids Resolution of Sister Chromatid Cohesion HSP90 chaperone cycle for steroid hormone receptors (SHR) in the presence of ligand Intraflagellar transport RHO GTPases Activate Formins COPI-mediated anterograde transport COPI-independent Golgi-to-ER retrograde traffic Mitotic Prometaphase HCMV Early Events Aggrephagy Aggrephagy EML4 and NUDC in mitotic spindle formation
Drugs
Diseases
GWAS		Blood protein levels ( 30072576)	Adult body size ( 32376654) Chronic inflammatory diseases (ankylosing spondylitis, Crohn's disease, psoriasis, primary sclerosing cholangitis, ulcerative colitis) (pleiotropy) ( 26974007) Crohn's disease ( 28067908) Early spontaneous preterm birth ( 31194736) Estimated glomerular filtration rate ( 31152163) Height ( 25282103 25429064 31562340) Hip circumference adjusted for BMI ( 34021172) Nonsyndromic cleft lip with cleft palate ( 28232668) Spherical equivalent or myopia (age of diagnosis) ( 29808027) Waist circumference adjusted for body mass index ( 34021172)
Interacting Genes		43 interacting genes: BCL2L11 BMF C12orf40 C14orf119 C17orf67 CHMP5 DLGAP1 DNAL4 DPPA3 DYNC1I1 EWSR1 F13A1 FAM117B GABARAPL2 GPHN GPRIN2 HDAC6 HMBOX1 HOMER3 HSF5 IHO1 KANK2 KIF2B MEOX2 MORN3 MSI2 MYO5A OTUD6A PAK1 PKIA PKIG PRKD3 RASGRP3 SECISBP2L SKAP1 SMCP SPAG8 STXBP4 THAP10 TLK1 TPPP XIAP ZAR1	3 interacting genes: CADPS DYNLL2 GOPC
Entrez ID		140735	339210
HPRD ID		06489	19273
Ensembl ID		ENSG00000264364	ENSG00000214226
Uniprot IDs		Q96FJ2	Q0P5P2
PDB IDs		2XQQ 3P8M 4D07
Enriched GO Terms of Interacting Partners?
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