DYNLL2 and CHMP5

		DYNLL2	CHMP5
Description		dynein light chain LC8-type 2	charged multivesicular body protein 5
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GO Annotations	Cellular Component	Nucleus Centrosome Cytosol Cytoplasmic Dynein Complex Microtubule Plasma Membrane Cilium Postsynaptic Density Membrane Dynein Complex Myosin V Complex Ciliary Tip 9+0 Non-motile Cilium Postsynapse Glutamatergic Synapse	Nucleus Multivesicular Body Cytosol Endosome Membrane Extracellular Exosome
	Molecular Function	Protein Binding Identical Protein Binding Protein-containing Complex Binding Dynein Intermediate Chain Binding Dynein Light Intermediate Chain Binding Scaffold Protein Binding	Protein Binding Cadherin Binding
	Biological Process	Microtubule-based Process Cilium Assembly	Regulation Of Receptor Recycling Vesicle Budding From Membrane Nucleus Organization Lysosome Organization Mitotic Metaphase Plate Congression Endosome To Lysosome Transport Regulation Of Centrosome Duplication Protein Transport Late Endosome To Vacuole Transport Via Multivesicular Body Sorting Pathway Multivesicular Body Assembly Viral Budding Midbody Abscission Cellular Response To Lipopolysaccharide Cellular Response To Muramyl Dipeptide Multivesicular Body Sorting Pathway Regulation Of Mitotic Spindle Assembly ESCRT III Complex Disassembly
Pathways		Activation of BMF and translocation to mitochondria Amplification of signal from unattached kinetochores via a MAD2 inhibitory signal Macroautophagy MHC class II antigen presentation Separation of Sister Chromatids Resolution of Sister Chromatid Cohesion HSP90 chaperone cycle for steroid hormone receptors (SHR) in the presence of ligand Intraflagellar transport RHO GTPases Activate Formins COPI-mediated anterograde transport COPI-independent Golgi-to-ER retrograde traffic Mitotic Prometaphase HCMV Early Events Aggrephagy Aggrephagy EML4 and NUDC in mitotic spindle formation	Budding and maturation of HIV virion Endosomal Sorting Complex Required For Transport (ESCRT)
Drugs
Diseases
GWAS		Blood protein levels ( 30072576)	Electrocardiogram morphology (amplitude at temporal datapoints) ( 32916098) Erectile dysfunction and prostate cancer treatment ( 20932654)
Interacting Genes		43 interacting genes: BCL2L11 BMF C12orf40 C14orf119 C17orf67 CHMP5 DLGAP1 DNAL4 DPPA3 DYNC1I1 EWSR1 F13A1 FAM117B GABARAPL2 GPHN GPRIN2 HDAC6 HMBOX1 HOMER3 HSF5 IHO1 KANK2 KIF2B MEOX2 MORN3 MSI2 MYO5A OTUD6A PAK1 PKIA PKIG PRKD3 RASGRP3 SECISBP2L SKAP1 SMCP SPAG8 STXBP4 THAP10 TLK1 TPPP XIAP ZAR1	19 interacting genes: APPBP2 CHMP1B CHMP4A CHMP4B DOP1B DYNLL2 GTF3A MITD1 NOD2 NUP98 PDCD10 RPL38 SMARCA4 STAMBP URGCP VPS4B VTA1 ZNF142 ZNF91
Entrez ID		140735	51510
HPRD ID		06489	15408
Ensembl ID		ENSG00000264364	ENSG00000086065
Uniprot IDs		Q96FJ2	Q9NZZ3
PDB IDs		2XQQ 3P8M 4D07	2LXM 3ULY 3UM0 3UM1 3UM2 4TXR
Enriched GO Terms of Interacting Partners?
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