CCDC197 and FMNL2

Number of citations of the paper that reports this interaction (PubMedID 32296183)
86

		CCDC197	FMNL2
Description		coiled-coil domain containing 197	formin like 2
Image		No pdb structure
GO Annotations	Cellular Component		Cytosol
	Molecular Function	Protein Binding	Small GTPase Binding Cadherin Binding Actin Filament Binding
	Biological Process		Cytoskeleton Organization Regulation Of Cell Shape Cell Migration Regulation Of Cell Morphogenesis Cortical Actin Cytoskeleton Organization
Pathways			RHO GTPases Activate Formins RHOC GTPase cycle CDC42 GTPase cycle
Drugs
Diseases
GWAS		Fish consumption ( 32895509)	Asthma (childhood onset) ( 27611488) Corneal astigmatism ( 30306274) Glaucoma ( 30054594) Glaucoma (primary open-angle) ( 33627673 29891935) Heel bone mineral density ( 30598549) Intraocular pressure ( 29617998 29785010 31959993 30054594 29235454) Lymphocyte counts ( 32888494) Refractive astigmatism ( 30306274) Vertical cup-disc ratio (adjusted for vertical disc diameter) ( 31959993) White blood cell count ( 32888494)
Interacting Genes		18 interacting genes: BEX2 C1orf216 CCDC146 CCHCR1 CYTH4 DISC1 FMNL2 KRT3 KRT75 LCA5L NTAQ1 NXF1 RUNX1T1 SKA1 SMARCD1 TXN2 USHBP1 WASHC3	13 interacting genes: AP1B1 AP2B1 APP ARL6IP6 CCDC197 CDC42 KRT27 MIPOL1 NECAB1 PNMA1 PRPF40A SUOX TXN2
Entrez ID		256369	114793
HPRD ID		12651	13545
Ensembl ID		ENSG00000175699	ENSG00000157827
Uniprot IDs			Q96PY5
PDB IDs			4YC7
Enriched GO Terms of Interacting Partners?
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