FMNL2 and CCDC197

Number of citations of the paper that reports this interaction (PubMedID 32296183)
86

		FMNL2	CCDC197
Description		formin like 2	coiled-coil domain containing 197
Image			No pdb structure
GO Annotations	Cellular Component	Cytosol
	Molecular Function	Small GTPase Binding Cadherin Binding Actin Filament Binding	Protein Binding
	Biological Process	Cytoskeleton Organization Regulation Of Cell Shape Cell Migration Regulation Of Cell Morphogenesis Cortical Actin Cytoskeleton Organization
Pathways		RHO GTPases Activate Formins RHOC GTPase cycle CDC42 GTPase cycle
Drugs
Diseases
GWAS		Asthma (childhood onset) ( 27611488) Corneal astigmatism ( 30306274) Glaucoma ( 30054594) Glaucoma (primary open-angle) ( 33627673 29891935) Heel bone mineral density ( 30598549) Intraocular pressure ( 29617998 29785010 31959993 30054594 29235454) Lymphocyte counts ( 32888494) Refractive astigmatism ( 30306274) Vertical cup-disc ratio (adjusted for vertical disc diameter) ( 31959993) White blood cell count ( 32888494)	Fish consumption ( 32895509)
Interacting Genes		13 interacting genes: AP1B1 AP2B1 APP ARL6IP6 CCDC197 CDC42 KRT27 MIPOL1 NECAB1 PNMA1 PRPF40A SUOX TXN2	18 interacting genes: BEX2 C1orf216 CCDC146 CCHCR1 CYTH4 DISC1 FMNL2 KRT3 KRT75 LCA5L NTAQ1 NXF1 RUNX1T1 SKA1 SMARCD1 TXN2 USHBP1 WASHC3
Entrez ID		114793	256369
HPRD ID		13545	12651
Ensembl ID		ENSG00000157827	ENSG00000175699
Uniprot IDs		Q96PY5
PDB IDs		4YC7
Enriched GO Terms of Interacting Partners?
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