FMNL2 and NECAB1

Number of citations of the paper that reports this interaction (PubMedID 32296183)
86

Data Source:
BioGRID (two hybrid)

		FMNL2	NECAB1
Description		formin like 2	N-terminal EF-hand calcium binding protein 1
Image			No pdb structure
GO Annotations	Cellular Component	Cytosol	Nucleoplasm Cytoplasm Cytosol
	Molecular Function	Small GTPase Binding Cadherin Binding Actin Filament Binding	Molecular_function Calcium Ion Binding Protein Binding Identical Protein Binding
	Biological Process	Cytoskeleton Organization Regulation Of Cell Shape Cell Migration Regulation Of Cell Morphogenesis Cortical Actin Cytoskeleton Organization	Blastocyst Hatching Biological_process Regulation Of Amyloid Precursor Protein Biosynthetic Process
Pathways		RHO GTPases Activate Formins RHOC GTPase cycle CDC42 GTPase cycle
Drugs
Diseases
GWAS		Asthma (childhood onset) ( 27611488) Corneal astigmatism ( 30306274) Glaucoma ( 30054594) Glaucoma (primary open-angle) ( 33627673 29891935) Heel bone mineral density ( 30598549) Intraocular pressure ( 29617998 29785010 31959993 30054594 29235454) Lymphocyte counts ( 32888494) Refractive astigmatism ( 30306274) Vertical cup-disc ratio (adjusted for vertical disc diameter) ( 31959993) White blood cell count ( 32888494)	Age at first sexual intercourse ( 34211149)
Interacting Genes		13 interacting genes: AP1B1 AP2B1 APP ARL6IP6 CCDC197 CDC42 KRT27 MIPOL1 NECAB1 PNMA1 PRPF40A SUOX TXN2	19 interacting genes: AP1M1 APP ATOX1 BHLHA9 BRPF1 CDC37 CPNE4 CPNE7 CPNE8 DAPK1 DISC1 FMNL2 LNX1 MORF4L1 NECAB2 PAX4 SNX11 TCEA2 TCEANC
Entrez ID		114793	64168
HPRD ID		13545	16851
Ensembl ID		ENSG00000157827	ENSG00000123119
Uniprot IDs		Q96PY5	Q8N987
PDB IDs		4YC7
Enriched GO Terms of Interacting Partners?
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