SMG5 and CKB

		SMG5	CKB
Description		SMG5 nonsense mediated mRNA decay factor	creatine kinase B
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GO Annotations	Cellular Component	Nucleus Telomerase Holoenzyme Complex Cytoplasm Cytosol	Extracellular Space Nucleus Mitochondrion Cytosol Dendrite Neuronal Cell Body Extracellular Exosome
	Molecular Function	Protein Binding Ubiquitin Protein Ligase Binding Telomeric DNA Binding Histone Deacetylase Binding Protein Phosphatase 2A Binding Telomerase RNA Binding	Creatine Kinase Activity Protein Binding ATP Binding Kinase Activity Ubiquitin Protein Ligase Binding
	Biological Process	Nuclear-transcribed MRNA Catabolic Process, Nonsense-mediated Decay MRNA Export From Nucleus Regulation Of Telomere Maintenance Regulation Of Telomere Maintenance Via Telomerase Regulation Of Dephosphorylation	Phosphorylation Cerebellum Development Substantia Nigra Development Cellular Chloride Ion Homeostasis Phosphocreatine Biosynthetic Process
Pathways		Nonsense Mediated Decay (NMD) enhanced by the Exon Junction Complex (EJC)	Creatine metabolism RND3 GTPase cycle
Drugs			Creatine Phosphocreatine
Diseases
GWAS		Glycated hemoglobin levels ( 29170429) Hemoglobin A1c levels ( 29403010) Mean corpuscular hemoglobin concentration ( 29403010 20139978)	Adult body size ( 32376654) Autism spectrum disorder or schizophrenia ( 28540026) Body mass index ( 26426971) Brain morphology (MOSTest) ( 32665545) Coronary artery disease ( 29212778) Extremely high intelligence ( 29520040) Height ( 28552196 31562340) Schizophrenia ( 25056061)
Interacting Genes		9 interacting genes: APP CKB PLEKHO1 SMG1 SMG6 SMG7 STUB1 TERT UPF1	27 interacting genes: ACD ARIH2 ASB9 CKM DIO3 DNAH5 EML1 ERBB2 EVL FUT8 GOLGA2 GPR65 IFI27 ILK JAG2 MLH1 OGT POT1 PPP1CA PSEN1 SERP2 SMG5 TAB1 TERF1 TINF2 TRIM63 UBE3A
Entrez ID		23381	1152
HPRD ID		16869	00423
Ensembl ID		ENSG00000198952	ENSG00000166165
Uniprot IDs		Q9UPR3	G3V4N7 P12277 V9HWH2
PDB IDs		2HWY	3B6R 3DRB 3DRE 6V9H
Enriched GO Terms of Interacting Partners?
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