SMG5

Description		SMG5 nonsense mediated mRNA decay factor
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GO Annotations	Cellular Component	Nucleus Telomerase Holoenzyme Complex Cytoplasm Cytosol
	Molecular Function	Protein Binding Ubiquitin Protein Ligase Binding Telomeric DNA Binding Histone Deacetylase Binding Protein Phosphatase 2A Binding Telomerase RNA Binding
	Biological Process	Nuclear-transcribed MRNA Catabolic Process, Nonsense-mediated Decay MRNA Export From Nucleus Regulation Of Telomere Maintenance Regulation Of Telomere Maintenance Via Telomerase Regulation Of Dephosphorylation
Pathways		Nonsense Mediated Decay (NMD) enhanced by the Exon Junction Complex (EJC)
Drugs
Diseases
GWAS		Glycated hemoglobin levels ( 29170429) Hemoglobin A1c levels ( 29403010) Mean corpuscular hemoglobin concentration ( 29403010 20139978)
Interacting Genes		9 interacting genes: APP CKB PLEKHO1 SMG1 SMG6 SMG7 STUB1 TERT UPF1
Entrez ID		23381
HPRD ID		16869
Ensembl ID		ENSG00000198952
Uniprot IDs		Q9UPR3
PDB IDs		2HWY
Enriched GO Terms of Interacting Partners?
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