CKB and SMG5

		CKB	SMG5
Description		creatine kinase B	SMG5 nonsense mediated mRNA decay factor
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GO Annotations	Cellular Component	Extracellular Space Nucleus Mitochondrion Cytosol Dendrite Neuronal Cell Body Extracellular Exosome	Nucleus Telomerase Holoenzyme Complex Cytoplasm Cytosol
	Molecular Function	Creatine Kinase Activity Protein Binding ATP Binding Kinase Activity Ubiquitin Protein Ligase Binding	Protein Binding Ubiquitin Protein Ligase Binding Telomeric DNA Binding Histone Deacetylase Binding Protein Phosphatase 2A Binding Telomerase RNA Binding
	Biological Process	Phosphorylation Cerebellum Development Substantia Nigra Development Cellular Chloride Ion Homeostasis Phosphocreatine Biosynthetic Process	Nuclear-transcribed MRNA Catabolic Process, Nonsense-mediated Decay MRNA Export From Nucleus Regulation Of Telomere Maintenance Regulation Of Telomere Maintenance Via Telomerase Regulation Of Dephosphorylation
Pathways		Creatine metabolism RND3 GTPase cycle	Nonsense Mediated Decay (NMD) enhanced by the Exon Junction Complex (EJC)
Drugs		Creatine Phosphocreatine
Diseases
GWAS		Adult body size ( 32376654) Autism spectrum disorder or schizophrenia ( 28540026) Body mass index ( 26426971) Brain morphology (MOSTest) ( 32665545) Coronary artery disease ( 29212778) Extremely high intelligence ( 29520040) Height ( 28552196 31562340) Schizophrenia ( 25056061)	Glycated hemoglobin levels ( 29170429) Hemoglobin A1c levels ( 29403010) Mean corpuscular hemoglobin concentration ( 29403010 20139978)
Interacting Genes		27 interacting genes: ACD ARIH2 ASB9 CKM DIO3 DNAH5 EML1 ERBB2 EVL FUT8 GOLGA2 GPR65 IFI27 ILK JAG2 MLH1 OGT POT1 PPP1CA PSEN1 SERP2 SMG5 TAB1 TERF1 TINF2 TRIM63 UBE3A	9 interacting genes: APP CKB PLEKHO1 SMG1 SMG6 SMG7 STUB1 TERT UPF1
Entrez ID		1152	23381
HPRD ID		00423	16869
Ensembl ID		ENSG00000166165	ENSG00000198952
Uniprot IDs		G3V4N7 P12277 V9HWH2	Q9UPR3
PDB IDs		3B6R 3DRB 3DRE 6V9H	2HWY
Enriched GO Terms of Interacting Partners?
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