CKB and EVL

		CKB	EVL
Description		creatine kinase B	Enah/Vasp-like
Image			No pdb structure
GO Annotations	Cellular Component	Extracellular Space Nucleus Mitochondrion Cytosol Dendrite Neuronal Cell Body Extracellular Exosome	Cytoplasm Cytosol Cytoskeleton Focal Adhesion Membrane Lamellipodium
	Molecular Function	Creatine Kinase Activity Protein Binding ATP Binding Kinase Activity Ubiquitin Protein Ligase Binding	Actin Binding Protein Binding Profilin Binding SH3 Domain Binding
	Biological Process	Phosphorylation Cerebellum Development Substantia Nigra Development Cellular Chloride Ion Homeostasis Phosphocreatine Biosynthetic Process	Actin Filament Organization Cell Surface Receptor Signaling Pathway Nervous System Development Actin Polymerization Or Depolymerization Animal Organ Morphogenesis Negative Regulation Of Epithelial Cell Migration Positive Regulation Of Actin Filament Polymerization Actin Nucleation Protein Homotetramerization Positive Regulation Of Stress Fiber Assembly Negative Regulation Of Ruffle Assembly
Pathways		Creatine metabolism RND3 GTPase cycle	Generation of second messenger molecules Signaling by ROBO receptors Signaling by ROBO receptors RHO GTPases Activate Formins
Drugs		Creatine Phosphocreatine
Diseases
GWAS		Adult body size ( 32376654) Autism spectrum disorder or schizophrenia ( 28540026) Body mass index ( 26426971) Brain morphology (MOSTest) ( 32665545) Coronary artery disease ( 29212778) Extremely high intelligence ( 29520040) Height ( 28552196 31562340) Schizophrenia ( 25056061)	Blood protein levels ( 30072576) White matter hyperintensities ( 32358547) White matter hyperintensity burden ( 25663218)
Interacting Genes		27 interacting genes: ACD ARIH2 ASB9 CKM DIO3 DNAH5 EML1 ERBB2 EVL FUT8 GOLGA2 GPR65 IFI27 ILK JAG2 MLH1 OGT POT1 PPP1CA PSEN1 SERP2 SMG5 TAB1 TERF1 TINF2 TRIM63 UBE3A	45 interacting genes: ABI1 ABI3 ABL1 APBB1 APBB1IP ATG2B BDKRB1 BEGAIN C14orf132 CKB CRKL DNMBP ENAH F11R FXR1 FXR2 FYB1 FYN GSKIP HCK HTT KRT17 KRT34 LRP1B LYN PFN2 POT1 PRPF40A RAD51 SEMA6A SH3RF1 SPTA1 SPTAN1 SRC TCERG1 TERF1 TES TRIM9 VASP WAS WASL XIRP1 ZDHHC17 ZNF655 ZYX
Entrez ID		1152	51466
HPRD ID		00423	10942
Ensembl ID		ENSG00000166165	ENSG00000196405
Uniprot IDs		G3V4N7 P12277 V9HWH2	A0A024R6K5 Q9UI08
PDB IDs		3B6R 3DRB 3DRE 6V9H
Enriched GO Terms of Interacting Partners?
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