SYNE2 and MAPK3

  • Number of citations of the paper that reports this interaction (PubMedID 19861416)
  • 26
  • Data Source:
  • BioGRID (pull down, affinity chromatography technology)

SYNE2

MAPK3

Description spectrin repeat containing nuclear envelope protein 2 mitogen-activated protein kinase 3
Image
GO Annotations Cellular Component
Molecular Function
Biological Process
Pathways
Drugs
Diseases
GWAS
  • Anorexia nervosa, attention-deficit/hyperactivity disorder, autism spectrum disorder, bipolar disorder, major depression, obsessive-compulsive disorder, schizophrenia, or Tourette syndrome (pleiotropy) ( 31835028)
  • Atrial fibrillation ( 28416818 30061737 29892015 22544366)
  • Blond vs. brown/black hair color ( 30531825)
  • Cutaneous malignant melanoma ( 32341527)
  • Cutaneous melanoma or hair colour ( 32341527)
  • Depression ( 29700475)
  • HDL cholesterol levels ( 32109663)
  • Metabolite levels ( 23823483)
  • Nevus count or cutaneous melanoma ( 32341527 30429480)
  • PR interval ( 32439900)
  • Psoriasis ( 25854761)
  • Pulmonary function decline ( 22424883)
  • Serum metabolite concentrations in chronic kidney disease ( 29545352)
  • Serum metabolite levels ( 33031748)
  • Serum metabolite ratios in chronic kidney disease ( 29545352)
  • Sphingomyelin levels ( 31551469)
  • Youthful appearance (self-reported) ( 32339537)
Interacting Genes 14 interacting genes: ABI1 ACTC1 BRAP CALM1 ESR2 GLE1 MAPK3 MAPK8IP2 MEOX2 MTNR1B NR2C1 PML SASH1 UBC 187 interacting genes: AKR1C1 AMOT ARRB1 ATP1A1 AURKA BCL2 BCL3 BRAF BTBD10 BUB1 C1QBP CASP8 CASP9 CAV1 CCDC6 CDC23 CDC25C CDC45 CDH1 CDKN2A CEBPB CPXM1 CREBBP CREM CRP CTNND1 CUEDC2 DAPK1 DCC DCP1A DCP2 DLC1 DUSP1 DUSP10 DUSP3 DUSP4 DUSP5 DUSP6 DUSP9 EGFR ELK1 ELK4 EPOR ESR1 ETS1 ETV1 FBXW7 FCGR2B FKBP2 FOS FOXP2 FRS2 GAB1 GAB2 GATA1 GATA4 GJA1 GMFB GRK2 GTF2I HDAC4 HDAC6 HIF1A HMMR HNF4A HSF1 HSF4 HSPB8 HTRA2 ID2 IER3 INSR IRS1 ITGAV ITGB3 JUN JUND KRT8 KSR2 L3MBTL3 LAMTOR3 LCK LIPE LRPAP1 LRRC4 LYN MAFG MAGEA11 MAGED1 MAP2K1 MAP2K2 MAP2K3 MAP3K14 MAPK14 MAPK8 MAPKAPK2 MAPT MBP MED1 METAP2 MKNK1 MYC MYLK MYOG NAB2 NCKIPSD NGFR NRAS NTRK1 NTRK3 NUP153 NUP58 PAK2 PDE6G PDGFRL PEA15 PFKM PLAT PLCB1 PPARA PPP1CA PPP2CA PRKCD PRKCE PRKCZ PTPN11 PTPN5 PTPN7 PTPRE PTPRR PXN RAB4A RAF1 RALGDS RB1 RCAN1 RET RNF114 RPS6KA1 RPS6KA2 RPS6KA3 RPS6KA4 RPS6KB1 RPTOR RXRA SCAND1 SCRIB SMAD2 SNCG SORBS3 SOS1 SOX2 SP1 SPIB SRC SREBF1 SREBF2 STAR STAT3 STAT5A STK11 STMN1 STMN2 STUB1 SULT4A1 SYK SYN1 SYNE2 TAL1 TAL2 TCF3 TGIF1 TH TNFSF11 TOP2B TP53 TRIM54 TSC2 TTYH3 UBE4B UBTF USP21 VDR VPS52 ZC3HC1 ZNF219 ZNF7
Entrez ID 23224 5595
HPRD ID 09763 03479
Ensembl ID ENSG00000054654 ENSG00000102882
Uniprot IDs Q6MZP0 Q8WXH0 L7RXH5 P27361 Q9BWJ1
PDB IDs 4DXS 4FI9 6XF1 2ZOQ 4QTB 6GES
Enriched GO Terms of Interacting Partners?
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