MAPK3 and RPS6KA2

  • Number of citations of the paper that reports this interaction (PubMedID 8939914)
  • 46
  • Data Source:
  • BioGRID (proximity labelling technology)
  • HPRD (in vitro, in vivo)

MAPK3

RPS6KA2

Description mitogen-activated protein kinase 3 ribosomal protein S6 kinase A2
Image No pdb structure
GO Annotations Cellular Component
Molecular Function
Biological Process
Pathways
Drugs
Diseases
GWAS
  • 3-month functional outcome in ischaemic stroke (modified Rankin score) ( 30796134)
  • Alzheimer's disease progression score ( 29860282)
  • Bipolar disorder ( 31043756)
  • Bipolar I disorder ( 31043756)
  • Blood pressure (smoking interaction) ( 25189868)
  • Café-au-lait macule number in neurofibromatosis type1 ( 32869517)
  • Dental caries ( 23259602)
  • HDL cholesterol levels in HIV infection ( 33109212)
  • Inflammatory bowel disease ( 27569725 23128233)
  • Macrovascular complications in type 2 diabetes ( 33430853)
  • Pre-treatment viral load in HIV-1 infection ( 31219150)
  • Smooth-surface caries ( 24556642)
  • Urinary metabolite levels in chronic kidney disease ( 31959995)
  • Waist circumference ( 28552196)
Interacting Genes 187 interacting genes: AKR1C1 AMOT ARRB1 ATP1A1 AURKA BCL2 BCL3 BRAF BTBD10 BUB1 C1QBP CASP8 CASP9 CAV1 CCDC6 CDC23 CDC25C CDC45 CDH1 CDKN2A CEBPB CPXM1 CREBBP CREM CRP CTNND1 CUEDC2 DAPK1 DCC DCP1A DCP2 DLC1 DUSP1 DUSP10 DUSP3 DUSP4 DUSP5 DUSP6 DUSP9 EGFR ELK1 ELK4 EPOR ESR1 ETS1 ETV1 FBXW7 FCGR2B FKBP2 FOS FOXP2 FRS2 GAB1 GAB2 GATA1 GATA4 GJA1 GMFB GRK2 GTF2I HDAC4 HDAC6 HIF1A HMMR HNF4A HSF1 HSF4 HSPB8 HTRA2 ID2 IER3 INSR IRS1 ITGAV ITGB3 JUN JUND KRT8 KSR2 L3MBTL3 LAMTOR3 LCK LIPE LRPAP1 LRRC4 LYN MAFG MAGEA11 MAGED1 MAP2K1 MAP2K2 MAP2K3 MAP3K14 MAPK14 MAPK8 MAPKAPK2 MAPT MBP MED1 METAP2 MKNK1 MYC MYLK MYOG NAB2 NCKIPSD NGFR NRAS NTRK1 NTRK3 NUP153 NUP58 PAK2 PDE6G PDGFRL PEA15 PFKM PLAT PLCB1 PPARA PPP1CA PPP2CA PRKCD PRKCE PRKCZ PTPN11 PTPN5 PTPN7 PTPRE PTPRR PXN RAB4A RAF1 RALGDS RB1 RCAN1 RET RNF114 RPS6KA1 RPS6KA2 RPS6KA3 RPS6KA4 RPS6KB1 RPTOR RXRA SCAND1 SCRIB SMAD2 SNCG SORBS3 SOS1 SOX2 SP1 SPIB SRC SREBF1 SREBF2 STAR STAT3 STAT5A STK11 STMN1 STMN2 STUB1 SULT4A1 SYK SYN1 SYNE2 TAL1 TAL2 TCF3 TGIF1 TH TNFSF11 TOP2B TP53 TRIM54 TSC2 TTYH3 UBE4B UBTF USP21 VDR VPS52 ZC3HC1 ZNF219 ZNF7 19 interacting genes: AFDN BAD CREB1 DYNLT1 DYNLT2 FLNC FOS JUN KCNJ6 L1CAM MAGI1 MAP2K1 MAPK1 MAPK3 OTUD4 SHANK1 TBXT THBS2 TP53
Entrez ID 5595 6196
HPRD ID 03479 03403
Ensembl ID ENSG00000102882 ENSG00000071242
Uniprot IDs L7RXH5 P27361 Q9BWJ1 B7Z3B5 Q15349 X5D337
PDB IDs 2ZOQ 4QTB 6GES
Enriched GO Terms of Interacting Partners?
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