SYNE2 and PML

  • Number of citations of the paper that reports this interaction (PubMedID 19861416)
  • 26

SYNE2

PML

Description spectrin repeat containing nuclear envelope protein 2 PML nuclear body scaffold
Image
GO Annotations Cellular Component
Molecular Function
Biological Process
Pathways
Drugs
Diseases
GWAS
  • Anorexia nervosa, attention-deficit/hyperactivity disorder, autism spectrum disorder, bipolar disorder, major depression, obsessive-compulsive disorder, schizophrenia, or Tourette syndrome (pleiotropy) ( 31835028)
  • Atrial fibrillation ( 28416818 30061737 29892015 22544366)
  • Blond vs. brown/black hair color ( 30531825)
  • Cutaneous malignant melanoma ( 32341527)
  • Cutaneous melanoma or hair colour ( 32341527)
  • Depression ( 29700475)
  • HDL cholesterol levels ( 32109663)
  • Metabolite levels ( 23823483)
  • Nevus count or cutaneous melanoma ( 32341527 30429480)
  • PR interval ( 32439900)
  • Psoriasis ( 25854761)
  • Pulmonary function decline ( 22424883)
  • Serum metabolite concentrations in chronic kidney disease ( 29545352)
  • Serum metabolite levels ( 33031748)
  • Serum metabolite ratios in chronic kidney disease ( 29545352)
  • Sphingomyelin levels ( 31551469)
  • Youthful appearance (self-reported) ( 32339537)
  • Accelerometer-based physical activity measurement (fraction of time with accelerations >425 milli-gravities) ( 29899525)
  • Appendicular lean mass ( 33097823)
  • Birth weight ( 31043758)
  • Height ( 28552196 20881960 25282103)
  • Hip circumference adjusted for BMI ( 34021172)
  • Insomnia symptoms (never/rarely vs. sometimes/usually) ( 30804566)
  • Insomnia symptoms (never/rarely vs. usually) ( 30804566)
  • Myopia (pathological) ( 23049088)
  • Paget's disease ( 21623375)
  • Physical activity (overall physical activity time) ( 30531941)
  • White blood cell count ( 32888494)
Interacting Genes 14 interacting genes: ABI1 ACTC1 BRAP CALM1 ESR2 GLE1 MAPK3 MAPK8IP2 MEOX2 MTNR1B NR2C1 PML SASH1 UBC 112 interacting genes: ADH1B ANKRD2 ARID3A ARNT ATF2 ATXN1 AURKA AXIN1 BANP BCL2 BCL6 CASP8AP2 CCNT1 CDK1 CDK2 CDK6 CHFR CREBBP CSNK2A1 DAXX EGFR EIF4E ELF4 EP300 ERCC6 FOS FXR1 GATA1 GATA2 HDAC1 HDAC2 HDAC3 HHEX HIPK2 HTT JUN KAT5 KAT6A KLHL20 MAD1L1 MAPK11 MAPK14 MDM2 MED7 MXD1 MYB MYC NACC1 NCOA2 NCOR1 NCOR2 NFKB1 NR3C1 NR4A1 PAWR PAXIP1 PCBD2 PIAS1 PIAS2 PIN1 PLAGL1 PLSCR1 POLR2E PPARG PSMA3 RARA RB1 RBX1 RELA RNF111 RNF125 RPL11 RXRA SENP1 SENP2 SH3GL1 SIAH2 SIN3A SIRT1 SKI SLC27A2 SMAD3 SP1 SP100 SRF STAT3 SUMO1 SUMO2 SUMO3 SUV39H1 SYNE2 TDG TERF2IP TGFBR1 TGFBR2 TGIF1 THRA TOPBP1 TP53 TP63 TP73 TRIB3 TRIM24 TRIM27 TRIM69 UBE2I UBE2U UBE3A USP11 ZBTB16 ZFYVE9 ZNF451
Entrez ID 23224 5371
HPRD ID 09763 00023
Ensembl ID ENSG00000054654 ENSG00000140464
Uniprot IDs Q6MZP0 Q8WXH0 P29590
PDB IDs 4DXS 4FI9 6XF1 1BOR 2MVW 2MWX 4WJN 4WJO 5YUF 6IMQ 6UYO 6UYP 6UYQ 6UYR 6UYS 6UYT 6UYU 6UYV
Enriched GO Terms of Interacting Partners?
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