FLT1 and FLT3

FLT1

FLT3

Description fms related receptor tyrosine kinase 1 fms related receptor tyrosine kinase 3
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GO Annotations Cellular Component
Molecular Function
Biological Process
Pathways
Drugs
Diseases
GWAS
  • Acute respiratory distress syndrome in sepsis ( 31982041)
  • Birth weight ( 31043758)
  • Body mass index ( 26426971)
  • Cognitive performance ( 19734545)
  • Coronary artery disease ( 32469254 29212778 33020668)
  • Coronary artery disease (myocardial infarction, percutaneous transluminal coronary angioplasty, coronary artery bypass grafting, angina or chromic ischemic heart disease) ( 28714975)
  • Coronary heart disease ( 23364394)
  • Myocardial infarction ( 33532862)
  • Refractive error ( 32231278)
  • Spherical equivalent or myopia (age of diagnosis) ( 29808027)
  • Triglyceride levels ( 32203549)
Interacting Genes 33 interacting genes: ALOX5AP ARL2BP ATR CDK8 CRK CTNNB1 FLT3 FYN GRB2 HMGB1 KDR LATS2 MIPEP NCK1 NEDD4 NRP1 NRP2 PGF PIK3R1 PLCG1 PLCG2 PTK2 PTK2B PTPN11 RASSF9 SHC1 SHC2 SRPK1 STAT1 STAT3 VEGFA VEGFB YES1 25 interacting genes: CBL CBLB CDK8 ERBB2 FIZ1 FLT1 FLT3LG FMO1 GPR12 GRB2 IKBKG INPP5D NCK1 NFIB PNPLA3 PTPN11 PTPN12 PTPN6 SH3BP2 SHC1 SLA SNRPA1 SOCS1 SRC UBE2L6
Entrez ID 2321 2322
HPRD ID 01297 00635
Ensembl ID ENSG00000102755 ENSG00000122025
Uniprot IDs L7RSL3 P17948 P36888
PDB IDs 1FLT 1QSV 1QSZ 1QTY 1RV6 2XAC 3HNG 4CKV 4CL7 5ABD 5EX3 5T89 1RJB 3QS7 3QS9 4RT7 4XUF 5X02 6IL3 6JQR
Enriched GO Terms of Interacting Partners?
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