FLT1 and CRK

  • Number of citations of the paper that reports this interaction (PubMedID 9722576)
  • 27
  • Data Source:
  • HPRD (in vitro)

FLT1

CRK

Description fms related receptor tyrosine kinase 1 CRK proto-oncogene, adaptor protein
Image
GO Annotations Cellular Component
Molecular Function
Biological Process
Pathways
Drugs
Diseases
GWAS
  • Acute respiratory distress syndrome in sepsis ( 31982041)
  • Birth weight ( 31043758)
  • Body mass index ( 26426971)
  • Cognitive performance ( 19734545)
  • Coronary artery disease ( 32469254 29212778 33020668)
  • Coronary artery disease (myocardial infarction, percutaneous transluminal coronary angioplasty, coronary artery bypass grafting, angina or chromic ischemic heart disease) ( 28714975)
  • Coronary heart disease ( 23364394)
  • Myocardial infarction ( 33532862)
  • Refractive error ( 32231278)
  • Spherical equivalent or myopia (age of diagnosis) ( 29808027)
  • Triglyceride levels ( 32203549)
Interacting Genes 33 interacting genes: ALOX5AP ARL2BP ATR CDK8 CRK CTNNB1 FLT3 FYN GRB2 HMGB1 KDR LATS2 MIPEP NCK1 NEDD4 NRP1 NRP2 PGF PIK3R1 PLCG1 PLCG2 PTK2 PTK2B PTPN11 RASSF9 SHC1 SHC2 SRPK1 STAT1 STAT3 VEGFA VEGFB YES1 169 interacting genes: ABL1 ABL2 ANKZF1 ANLN AR ARHGAP17 ARHGAP32 ASAP1 ASAP3 ASCL4 ATF3 ATXN1 AVIL BATF3 BCAR1 BCR BEX5 BUB1 C1orf94 C1QBP C4orf17 C6orf141 CBL CBLB CBLC CHTF18 CLNK CNDP2 CORO6 CRKL DAB1 DOCK1 DOCK3 DOK1 DOK2 DOK3 DOK4 DOK7 DPPA4 EFS EGFR ELK1 ELK3 EPHA3 EPHB2 EPHB3 EPHB6 EPS15 EPYC ERBB2 ERBB3 ERBB4 ESD EYA3 FASLG FER FGFR1 FLACC1 FLT1 FRS2 FSTL1 FYN GAB1 GABPB2 GAREM1 GRB2 HABP4 HSH2D IFT140 IGF1R IKZF3 INO80E INSR IRS1 IRS2 IRS4 ISL1 KCTD13 KCTD17 KDR KHDRBS1 KIT KLF15 KLHL20 LASP1 LHX8 LNX2 MAGEC3 MAP4K1 MAP4K5 MAPK4 MAPK8 MET MICAL1 MNDA MPG MYLIP MYOZ2 NCK1 NEDD9 NTRK1 NUFIP2 OFCC1 PAFAH1B2 PDGFRA PDGFRB PHC2 PIK3R1 PIK3R2 PIK3R3 PLSCR1 POT1 PPFIBP2 PPP1CA PRKACA PRRC2B PRRG2 PSMC1 PSMC6 PTK2 PTK2B PTPN1 PTPN4 PTPRH PTTG1 PXN RAB2B RAPGEF1 REPS1 RET RTCB RYBP SASH1 SAXO1 SEMA4D SEPTIN6 SETD9 SH2D2A SH3BP1 SHB SHC1 SOCS1 SOCS6 SOS1 SPRR2A STAT4 STAT5A STAT5B STRN4 SYN1 TCAP TDG TERF2IP TM4SF19 TP53 TP53BP2 TUBA1C TWIST2 TXK USP53 VAC14 VAV1 WASF1 WDR83 WEE1 XPO1 ZAP70 ZKSCAN7 ZNF557
Entrez ID 2321 1398
HPRD ID 01297 01267
Ensembl ID ENSG00000102755 ENSG00000167193
Uniprot IDs L7RSL3 P17948 A0A0S2Z3K9 A0A0S2Z3Q4 L7RT18 P46108
PDB IDs 1FLT 1QSV 1QSZ 1QTY 1RV6 2XAC 3HNG 4CKV 4CL7 5ABD 5EX3 5T89 1JU5 2DVJ 2EYV 2EYW 2EYX 2EYY 2EYZ 2MS4 5UL6 6ATV
Enriched GO Terms of Interacting Partners?
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