FLT3 and INPP5D

  • Number of citations of the paper that reports this interaction (PubMedID 9918857)
  • 18
  • Data Source:
  • HPRD (in vivo)

FLT3

INPP5D

Description fms related receptor tyrosine kinase 3 inositol polyphosphate-5-phosphatase D
Image
GO Annotations Cellular Component
Molecular Function
Biological Process
Pathways
Drugs
Diseases
GWAS
  • Allergic disease (asthma, hay fever or eczema) ( 29083406)
  • Alzheimer's disease (late onset) ( 30617256 24162737)
  • Alzheimer's disease or family history of Alzheimer's disease ( 30617256)
  • Contrast sensitivity ( 24152035)
  • Crohn's disease ( 22412388 23128233)
  • Eosinophil counts ( 32888494 27863252)
  • Eosinophil percentage of granulocytes ( 27863252)
  • Eosinophil percentage of white cells ( 32888494 27863252)
  • Family history of Alzheimer's disease ( 30617256)
  • High light scatter reticulocyte count ( 32888494)
  • High light scatter reticulocyte percentage of red cells ( 32888494)
  • Immature fraction of reticulocytes ( 32888494)
  • Monocyte count ( 32888494)
  • Neutrophil count ( 32888494)
  • Neutrophil percentage of granulocytes ( 27863252)
  • Perceived unattractiveness to mosquitoes ( 28199695)
  • Response to bronchodilator in chronic obstructive pulmonary disease (change in FEV1) ( 26503814)
  • Serum alkaline phosphatase levels ( 33547301)
  • Sum eosinophil basophil counts ( 27863252)
Interacting Genes 25 interacting genes: CBL CBLB CDK8 ERBB2 FIZ1 FLT1 FLT3LG FMO1 GPR12 GRB2 IKBKG INPP5D NCK1 NFIB PNPLA3 PTPN11 PTPN12 PTPN6 SH3BP2 SHC1 SLA SNRPA1 SOCS1 SRC UBE2L6 46 interacting genes: ARAP1 CD22 CD300LF CRKL CSF1R CSF3R CYSRT1 DAB1 DAB2 DOK1 DOK2 DOK3 EPOR FCGR1B FCGR2B FGR FLT3 GAB1 GAB2 GRB2 HCK IL4R JAK1 JAK3 KHDRBS3 KIT KRT31 KRT40 KRTAP1-3 KRTAP10-3 KRTAP10-7 KRTAP10-9 KRTAP6-3 LILRB4 LYN MET NOTCH2NLA PAX6 PECAM1 PLCG1 PTPN11 SH3KBP1 SHC1 SLAMF1 XIAP ZDHHC17
Entrez ID 2322 3635
HPRD ID 00635 09033
Ensembl ID ENSG00000122025 ENSG00000168918
Uniprot IDs P36888 Q92835
PDB IDs 1RJB 3QS7 3QS9 4RT7 4XUF 5X02 6IL3 6JQR 2YSX 5RW2 5RW3 5RW4 5RW5 5RW6 5RW7 5RW8 5RW9 5RWA 5RWB 5RWC 5RWD 5RWE 5RWF 5RWG 5RWH 5RWI 5RWJ 5RWK 5RWL 5RWM 5RWN 5RWO 5RWP 5RWQ 5RWR 5RWS 5RWT 5RWU 5RWV 5RWW 5RWX 5RWY 5RWZ 5RX0 5RX1 5RX2 5RX3 5RX4 5RX5 5RX6 5RX7 5RX8 5RX9 5RXA 5RXB 5RXC 5RXD 5RXE 5RXF 5RXG 5RXH 5RXI 5RXJ 5RXK 5RXL 5RXM 5RXO 5RXP 5RXQ 5RXR 5RXS 5RXT 5RXU 5RXV 5RXW 5RXX 5RXY 5RXZ 5RY0 5RY1 5RY2 5RY3 5RY4 5RY5 5RY6 5RY7 5RY8 5RY9 5RYA 5RYB 5RYC 5RYD 5RYE 5RYF 5RYG 5RYH 5RYI 5RYJ 5RYK 5RYL 6IBD 6XY7
Enriched GO Terms of Interacting Partners?
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