SEPTIN6 and SEPTIN2

Number of citations of the paper that reports this interaction (PubMedID 16189514)
1103

Data Source:
BioGRID (affinity chromatography technology, biochemical, affinity chromatography technology)
HPRD (in vitro, two hybrid)

		SEPTIN6	SEPTIN2
Description		septin 6	septin 2
Image
GO Annotations	Cellular Component	Kinetochore Spindle Septin Ring Synaptic Vesicle Microtubule Cytoskeleton Midbody Septin Complex Cell Division Site Cleavage Furrow Septin Collar Axon Terminus Sperm Annulus	Exocyst Kinetochore Nucleus Nucleoplasm Cytoplasm Spindle Plasma Membrane Axoneme Cell Cortex Septin Ring Synaptic Vesicle Actin Cytoskeleton Microtubule Cytoskeleton Midbody Septin Complex Cell Division Site Cleavage Furrow Photoreceptor Connecting Cilium Intercellular Bridge Perinuclear Region Of Cytoplasm Ciliary Membrane Extracellular Exosome Sperm Annulus Non-motile Cilium
	Molecular Function	GTPase Activity Protein Binding GTP Binding Molecular Adaptor Activity	GTPase Activity Protein Binding GTP Binding Cadherin Binding Molecular Adaptor Activity
	Biological Process	Mitotic Cytokinesis Spermatogenesis Cell Differentiation Cellular Protein Localization Cilium Assembly Cytoskeleton-dependent Cytokinesis	Smoothened Signaling Pathway Spermatogenesis Regulation Of Exocytosis Neuron Projection Development Cellular Protein Localization Cilium Assembly Cytoskeleton-dependent Cytokinesis
Pathways			Anchoring of the basal body to the plasma membrane
Drugs
Diseases
GWAS			Liver enzyme levels (alkaline phosphatase) ( 33972514)
Interacting Genes		14 interacting genes: CDC42EP2 CDC42EP3 CRK KDM1A MORN4 NSD3 PLEKHF2 RHOU S100A4 SEPTIN1 SEPTIN2 SEPTIN9 SH3KBP1 TK1	24 interacting genes: ATP6V0D2 BAZ2B CDC42 COG4 COL6A3 CSNK2A1 DAZAP2 ESR1 FXR1 JPT2 MTOR NGEF PIK3R2 PLEKHF2 RNF31 S100A4 SEPTIN5 SEPTIN6 SEPTIN9 SH3KBP1 STMN1 STX1A TBC1D21 UBL5
Entrez ID		23157	4735
HPRD ID		06716	03297
Ensembl ID		ENSG00000125354	ENSG00000168385
Uniprot IDs		B1AMS2 Q14141 Q541S4 Q548C9	A0A384N6H6 Q15019
PDB IDs		2QAG 6UPA	2QA5 2QAG 2QNR 6UPA 6UPQ 6UPR
Enriched GO Terms of Interacting Partners?
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