SEPTIN2 and S100A4

Number of citations of the paper that reports this interaction (PubMedID 14531065)
3

Data Source:
HPRD (in vitro)

		SEPTIN2	S100A4
Description		septin 2	S100 calcium binding protein A4
Image
GO Annotations	Cellular Component	Exocyst Kinetochore Nucleus Nucleoplasm Cytoplasm Spindle Plasma Membrane Axoneme Cell Cortex Septin Ring Synaptic Vesicle Actin Cytoskeleton Microtubule Cytoskeleton Midbody Septin Complex Cell Division Site Cleavage Furrow Photoreceptor Connecting Cilium Intercellular Bridge Perinuclear Region Of Cytoplasm Ciliary Membrane Extracellular Exosome Sperm Annulus Non-motile Cilium	Extracellular Region Extracellular Space Nucleus Neuron Projection Perinuclear Region Of Cytoplasm Collagen-containing Extracellular Matrix Extracellular Exosome
	Molecular Function	GTPase Activity Protein Binding GTP Binding Cadherin Binding Molecular Adaptor Activity	RNA Binding Actin Binding Calcium Ion Binding Protein Binding Identical Protein Binding Transition Metal Ion Binding Calcium-dependent Protein Binding RAGE Receptor Binding
	Biological Process	Smoothened Signaling Pathway Spermatogenesis Regulation Of Exocytosis Neuron Projection Development Cellular Protein Localization Cilium Assembly Cytoskeleton-dependent Cytokinesis	Epithelial To Mesenchymal Transition Positive Regulation Of I-kappaB Kinase/NF-kappaB Signaling
Pathways		Anchoring of the basal body to the plasma membrane
Drugs			Trifluoperazine Copper
Diseases
GWAS		Liver enzyme levels (alkaline phosphatase) ( 33972514)	Blood protein levels ( 29875488) Pulse pressure ( 30578418)
Interacting Genes		24 interacting genes: ATP6V0D2 BAZ2B CDC42 COG4 COL6A3 CSNK2A1 DAZAP2 ESR1 FXR1 JPT2 MTOR NGEF PIK3R2 PLEKHF2 RNF31 S100A4 SEPTIN5 SEPTIN6 SEPTIN9 SH3KBP1 STMN1 STX1A TBC1D21 UBL5	28 interacting genes: ACTA1 ANXA2 BAG6 CCN3 CEP20 EGFR FCGR3A HSPB1 MDM2 METAP2 MYH10 MYH2 MYH4 MYH9 PPFIBP1 RHOU S100A1 S100B S100P SEPTIN2 SEPTIN6 SEPTIN7 SMAD3 SRPK2 TP53 TPM2 TPM3 UNC119
Entrez ID		4735	6275
HPRD ID		03297	15914
Ensembl ID		ENSG00000168385	ENSG00000196154
Uniprot IDs		A0A384N6H6 Q15019	P26447
PDB IDs		2QA5 2QAG 2QNR 6UPA 6UPQ 6UPR	1M31 2LNK 2MRD 2Q91 3C1V 3CGA 3KO0 3M0W 3ZWH 4CFQ 4CFR 4ETO 4HSZ 5LPU 6T58
Enriched GO Terms of Interacting Partners?
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