SEPTIN2 and ATP6V0D2

Number of citations of the paper that reports this interaction (PubMedID 32296183)
86

Data Source:
BioGRID (two hybrid)

		SEPTIN2	ATP6V0D2
Description		septin 2	ATPase H+ transporting V0 subunit d2
Image			No pdb structure
GO Annotations	Cellular Component	Exocyst Kinetochore Nucleus Nucleoplasm Cytoplasm Spindle Plasma Membrane Axoneme Cell Cortex Septin Ring Synaptic Vesicle Actin Cytoskeleton Microtubule Cytoskeleton Midbody Septin Complex Cell Division Site Cleavage Furrow Photoreceptor Connecting Cilium Intercellular Bridge Perinuclear Region Of Cytoplasm Ciliary Membrane Extracellular Exosome Sperm Annulus Non-motile Cilium	Lysosomal Membrane Early Endosome Endosome Membrane Membrane Apical Plasma Membrane Vacuolar Proton-transporting V-type ATPase Complex Phagocytic Vesicle Membrane Proton-transporting V-type ATPase, V0 Domain Plasma Membrane Proton-transporting V-type ATPase Complex Extracellular Exosome
	Molecular Function	GTPase Activity Protein Binding GTP Binding Cadherin Binding Molecular Adaptor Activity	Protein Binding Proton Transmembrane Transporter Activity
	Biological Process	Smoothened Signaling Pathway Spermatogenesis Regulation Of Exocytosis Neuron Projection Development Cellular Protein Localization Cilium Assembly Cytoskeleton-dependent Cytokinesis	Vacuolar Transport Vacuolar Acidification Regulation Of Macroautophagy Proton Transmembrane Transport
Pathways		Anchoring of the basal body to the plasma membrane	ROS and RNS production in phagocytes Insulin receptor recycling Transferrin endocytosis and recycling Amino acids regulate mTORC1 Ion channel transport
Drugs			Tiludronic acid
Diseases
GWAS		Liver enzyme levels (alkaline phosphatase) ( 33972514)	Adverse response to lamotrigine and phenytoin ( 22379998) Neutrophil count ( 32888494)
Interacting Genes		24 interacting genes: ATP6V0D2 BAZ2B CDC42 COG4 COL6A3 CSNK2A1 DAZAP2 ESR1 FXR1 JPT2 MTOR NGEF PIK3R2 PLEKHF2 RNF31 S100A4 SEPTIN5 SEPTIN6 SEPTIN9 SH3KBP1 STMN1 STX1A TBC1D21 UBL5	20 interacting genes: ADRM1 AGO3 ARID5A CENPP CRX IKZF3 INCA1 MEOX2 NDUFB8 NICN1 PAX6 PHF12 POMC RBM15B REL RIBC1 RPS3 RUSC1 SEPTIN2 ZNF474
Entrez ID		4735	245972
HPRD ID		03297	16522
Ensembl ID		ENSG00000168385	ENSG00000147614
Uniprot IDs		A0A384N6H6 Q15019	A0A024R991 Q8N8Y2
PDB IDs		2QA5 2QAG 2QNR 6UPA 6UPQ 6UPR
Enriched GO Terms of Interacting Partners?
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