SEPTIN6 and CDC42EP2

Number of citations of the paper that reports this interaction (PubMedID 11584266)
78

Data Source:
BioGRID (pull down)

		SEPTIN6	CDC42EP2
Description		septin 6	CDC42 effector protein 2
Image			No pdb structure
GO Annotations	Cellular Component	Kinetochore Spindle Septin Ring Synaptic Vesicle Microtubule Cytoskeleton Midbody Septin Complex Cell Division Site Cleavage Furrow Septin Collar Axon Terminus Sperm Annulus	Cytoplasm Cytosol Cytoskeleton Plasma Membrane Endomembrane System Microtubule Cytoskeleton Membrane Phagocytic Vesicle
	Molecular Function	GTPase Activity Protein Binding GTP Binding Molecular Adaptor Activity	Opioid Peptide Activity GTPase Activator Activity Protein Binding Small GTPase Binding
	Biological Process	Mitotic Cytokinesis Spermatogenesis Cell Differentiation Cellular Protein Localization Cilium Assembly Cytoskeleton-dependent Cytokinesis	Actin Filament Organization Rho Protein Signal Transduction Regulation Of Cell Shape Actin Cytoskeleton Organization Positive Regulation Of Actin Filament Polymerization Positive Regulation Of Pseudopodium Assembly Positive Regulation Of Protein-containing Complex Assembly Regulation Of Catalytic Activity Cellular Response To Interferon-gamma
Pathways			MAPK6/MAPK4 signaling CDC42 GTPase cycle RHOQ GTPase cycle
Drugs
Diseases
GWAS			Acne (severe) ( 24927181) Mean corpuscular hemoglobin ( 32888494) Mean corpuscular volume ( 32888494 27863252)
Interacting Genes		14 interacting genes: CDC42EP2 CDC42EP3 CRK KDM1A MORN4 NSD3 PLEKHF2 RHOU S100A4 SEPTIN1 SEPTIN2 SEPTIN9 SH3KBP1 TK1	11 interacting genes: ARHGAP26 CASS4 CDC42 COX5B NEDD9 NME7 PICK1 RHOQ SEPTIN6 SEPTIN7 SNCA
Entrez ID		23157	10435
HPRD ID		06716	09363
Ensembl ID		ENSG00000125354	ENSG00000149798
Uniprot IDs		B1AMS2 Q14141 Q541S4 Q548C9	O14613
PDB IDs		2QAG 6UPA
Enriched GO Terms of Interacting Partners?
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