PAXIP1 and TP53BP1

  • Number of citations of the paper that reports this interaction (PubMedID 14576432)
  • 277
  • Data Source:
  • HPRD (in vitro)

PAXIP1

TP53BP1

Description PAX interacting protein 1 tumor protein p53 binding protein 1
Image
GO Annotations Cellular Component
Molecular Function
Biological Process
Pathways
Drugs
Diseases
GWAS
  • Bladder cancer (smoking interaction) ( 24662972)
  • Metabolite levels ( 23823483)
  • Antibody level in response to infection ( 25758998)
  • Apolipoprotein A1 levels ( 32203549)
  • Cardiometabolic and hematological traits ( 27668658)
  • Eosinophil counts ( 32888494)
  • HDL cholesterol levels ( 32203549 30698716)
  • HDL cholesterol levels in current drinkers ( 30698716)
  • HDL cholesterol levels x alcohol consumption (drinkers vs non-drinkers) interaction (2df) ( 30698716)
  • HDL cholesterol levels x alcohol consumption (regular vs non-regular drinkers) interaction (2df) ( 30698716)
  • Hematocrit ( 32888494)
  • Hemoglobin ( 32888494)
  • Lipoprotein phospholipase A2 activity in cardiovascular disease ( 28753643)
  • Liver volume ( 34128465)
  • Lung cancer in ever smokers ( 28604730)
  • Mean corpuscular volume ( 32888494)
  • Triglyceride levels ( 30698716)
  • Triglyceride levels in current drinkers ( 30698716)
  • Triglyceride levels x alcohol consumption (drinkers vs non-drinkers) interaction (2df) ( 30698716)
  • Triglyceride levels x alcohol consumption (regular vs non-regular drinkers) interaction (2df) ( 30698716)
  • Triglycerides ( 27036123)
Interacting Genes 91 interacting genes: A2M APP ATP1B1 ATP1B3 BTBD16 BTBD6 C2orf42 CABYR CATSPERG CBX8 CCNDBP1 CIAO2B CLU COMTD1 CYB5R4 DCP1A DIS3L DNAJA1 DNAJB11 DYNC2H1 ECSIT EIF3I EIF5B EP300 EPB41L3 FAHD1 FBLN5 FUCA1 H2AX H3C1 HNRNPLL HSPA14 HSPA4L INTS7 LACTB MAPRE2 MAST1 MRPL33 MT-ND1 MT2A MTIF3 MTNR1A NOS3 NPC2 NUPR1 NXT1 PAGR1 PAX2 PCBP2 PCYT1B PGGHG PGM1 PIAS1 PIAS2 PKP4 PLCD1 PML POM121 PPHLN1 PPIA PPP2R5C PRDX6 PSMA6 RNF32 RPA1 RPL12 RPS20 RPS27A SCAMP5 SCCPDH SELENOV SH3GL2 SMAD2 SNX3 SOX30 SPAG4 SPATA18 SUGT1 SUZ12 TCN2 TECR TM2D3 TMEM120A TP53BP1 TRAPPC8 UMPS WDR48 XAGE1B ZBTB8A ZNF251 ZNF280B 59 interacting genes: ANKS1A ARAP1 ATM BCL6 BLM BRCA1 BRCA2 C10orf55 CCDC120 CCNB1 CDK1 CHEK1 CRB2 CREB5 DCLRE1A DCLRE1C DYNLL1 E2F1 EP300 GALNTL5 H2AC4 H2AX H4-16 H4C1 H4C14 HGS IFI16 KAT8 KDM1A KLHDC7B LIG4 MDC1 MEOX2 NCOA3 NEK1 NFKB1 NUDT16 OXER1 PARP1 PAXIP1 PCNT PITX1 POU6F2 PTEN RAD18 RAD50 RAD51 RBL1 RBL2 RELA SLC6A9 SPAG9 SUMO2 TFDP1 TLX3 TP53 UBAP2 USP28 VAC14
Entrez ID 22976 7158
HPRD ID 08491 05569
Ensembl ID ENSG00000157212 ENSG00000067369
Uniprot IDs Q6ZW49 A6NNK5 Q12888
PDB IDs 3SQD 1GZH 1KZY 1XNI 2G3R 2IG0 2LVM 2MWO 2MWP 3LGF 3LGL 3LH0 4CRI 4RG2 4X34 5ECG 5J26 5KGF 5Z78 5ZCJ 6CO1 6CO2 6IU7 6IUA 6MXX 6MXY 6MXZ 6MY0 6RML 6RMM 6UPT 6VA5 6VIP
Enriched GO Terms of Interacting Partners?
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