PAXIP1 and NOS3

  • Number of citations of the paper that reports this interaction (PubMedID 21163940)
  • 36
  • Data Source:
  • BioGRID (two hybrid)

PAXIP1

NOS3

Description PAX interacting protein 1 nitric oxide synthase 3
Image
GO Annotations Cellular Component
Molecular Function
Biological Process
Pathways
Drugs
Diseases
GWAS
  • Bladder cancer (smoking interaction) ( 24662972)
  • Metabolite levels ( 23823483)
  • Coronary artery disease ( 29212778 30104761 26343387)
  • Coronary artery disease (myocardial infarction, percutaneous transluminal coronary angioplasty, coronary artery bypass grafting, angina or chromic ischemic heart disease) ( 28714975)
  • Diastolic blood pressure ( 27841878 28739976 27618448)
  • Diastolic blood pressure (cigarette smoking interaction) ( 29455858)
  • Diastolic blood pressure x alcohol consumption interaction (2df test) ( 29912962)
  • Estimated glomerular filtration rate ( 31451708)
  • Eyebrow thickness ( 26926045)
  • Hypertension ( 27618448)
  • Mean arterial pressure ( 27618448)
  • Mean platelet volume ( 32888494)
  • Medication use (agents acting on the renin-angiotensin system) ( 31015401)
  • Medication use (beta blocking agents) ( 31015401)
  • Medication use (calcium channel blockers) ( 31015401)
  • Medication use (diuretics) ( 31015401)
  • Medication use (HMG CoA reductase inhibitors) ( 31015401)
  • Myocardial infarction ( 33532862)
  • Offspring birth weight ( 31043758)
  • Periventricular white matter hyperintensities ( 32517579)
  • Platelet distribution width ( 32888494)
  • Stroke ( 30383316)
  • Systolic blood pressure ( 27841878 27618448 30578418)
  • Systolic blood pressure (cigarette smoking interaction) ( 29455858)
  • Systolic blood pressure x alcohol consumption interaction (2df test) ( 29912962)
Interacting Genes 91 interacting genes: A2M APP ATP1B1 ATP1B3 BTBD16 BTBD6 C2orf42 CABYR CATSPERG CBX8 CCNDBP1 CIAO2B CLU COMTD1 CYB5R4 DCP1A DIS3L DNAJA1 DNAJB11 DYNC2H1 ECSIT EIF3I EIF5B EP300 EPB41L3 FAHD1 FBLN5 FUCA1 H2AX H3C1 HNRNPLL HSPA14 HSPA4L INTS7 LACTB MAPRE2 MAST1 MRPL33 MT-ND1 MT2A MTIF3 MTNR1A NOS3 NPC2 NUPR1 NXT1 PAGR1 PAX2 PCBP2 PCYT1B PGGHG PGM1 PIAS1 PIAS2 PKP4 PLCD1 PML POM121 PPHLN1 PPIA PPP2R5C PRDX6 PSMA6 RNF32 RPA1 RPL12 RPS20 RPS27A SCAMP5 SCCPDH SELENOV SH3GL2 SMAD2 SNX3 SOX30 SPAG4 SPATA18 SUGT1 SUZ12 TCN2 TECR TM2D3 TMEM120A TP53BP1 TRAPPC8 UMPS WDR48 XAGE1B ZBTB8A ZNF251 ZNF280B 48 interacting genes: A2M ACTN2 ACTN4 AGTR1 AKT1 APOE APP BDKRB2 BDNF CALM1 CAV1 CDC37 CEP55 EDNRB EFEMP1 EFEMP2 ELAVL1 ELAVL3 EXOC6 EXOSC1 FIS1 GCDH GOLGA2 H3-3A HSP90AA1 HTRA1 IKZF3 IMMT KANK2 MAGEA11 MAST1 MPRIP NMT1 NOSIP NOSTRIN PAXIP1 PI4K2A PPP2R5A PSEN1 PSEN2 RHEB RNF31 RNF32 SP1 ST13 TECR TXNDC11 UMPS
Entrez ID 22976 4846
HPRD ID 08491 01224
Ensembl ID ENSG00000157212 ENSG00000164867
Uniprot IDs Q6ZW49 A0S0A6 P29474
PDB IDs 3SQD 1M9J 1M9K 1M9M 1M9Q 1M9R 1NIW 2LL7 2MG5 2N8J 3EAH 3NOS 4D1O 4D1P 5UO8 5UO9 5UOA 5UOB 5UOC 5VVB 5VVC 5VVD 5XOF 6AV6 6AV7 6CIE 6CIF 6NH1 6NH2 6NH3 6NH4 6NH5 6NH6 6NH7 6NH8 6NHF 6POU 6POV 6POW 6POX 6POY 6POZ 6PP0 6PP1 6PP2 6PP3 6PP4
Enriched GO Terms of Interacting Partners?
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