TP53BP1 and E2F1

  • Number of citations of the paper that reports this interaction (PubMedID 8896460)
  • 19
  • Data Source:
  • HPRD (in vivo, in vitro)

TP53BP1

E2F1

Description tumor protein p53 binding protein 1 E2F transcription factor 1
Image
GO Annotations Cellular Component
Molecular Function
Biological Process
Pathways
Drugs
Diseases
GWAS
  • Antibody level in response to infection ( 25758998)
  • Apolipoprotein A1 levels ( 32203549)
  • Cardiometabolic and hematological traits ( 27668658)
  • Eosinophil counts ( 32888494)
  • HDL cholesterol levels ( 32203549 30698716)
  • HDL cholesterol levels in current drinkers ( 30698716)
  • HDL cholesterol levels x alcohol consumption (drinkers vs non-drinkers) interaction (2df) ( 30698716)
  • HDL cholesterol levels x alcohol consumption (regular vs non-regular drinkers) interaction (2df) ( 30698716)
  • Hematocrit ( 32888494)
  • Hemoglobin ( 32888494)
  • Lipoprotein phospholipase A2 activity in cardiovascular disease ( 28753643)
  • Liver volume ( 34128465)
  • Lung cancer in ever smokers ( 28604730)
  • Mean corpuscular volume ( 32888494)
  • Triglyceride levels ( 30698716)
  • Triglyceride levels in current drinkers ( 30698716)
  • Triglyceride levels x alcohol consumption (drinkers vs non-drinkers) interaction (2df) ( 30698716)
  • Triglyceride levels x alcohol consumption (regular vs non-regular drinkers) interaction (2df) ( 30698716)
  • Triglycerides ( 27036123)
Interacting Genes 59 interacting genes: ANKS1A ARAP1 ATM BCL6 BLM BRCA1 BRCA2 C10orf55 CCDC120 CCNB1 CDK1 CHEK1 CRB2 CREB5 DCLRE1A DCLRE1C DYNLL1 E2F1 EP300 GALNTL5 H2AC4 H2AX H4-16 H4C1 H4C14 HGS IFI16 KAT8 KDM1A KLHDC7B LIG4 MDC1 MEOX2 NCOA3 NEK1 NFKB1 NUDT16 OXER1 PARP1 PAXIP1 PCNT PITX1 POU6F2 PTEN RAD18 RAD50 RAD51 RBL1 RBL2 RELA SLC6A9 SPAG9 SUMO2 TFDP1 TLX3 TP53 UBAP2 USP28 VAC14 82 interacting genes: ARID3A ATAD2 ATM ATR BIN1 BIRC2 BRCA1 BRD2 BRMS1 BTRC CCNA1 CCNA2 CDK1 CDK2 CDK3 CDK7 CDKN2A CEBPE CHEK2 CREBBP CTDP1 CUL1 CUL2 DDB2 DIABLO E2F6 EP300 ERCC3 FHL2 GSK3B GTF2H1 HCFC1 IGF1 KAT5 KDM1A MDM4 MGA MNAT1 MPHOSPH10 MTA1 MYBL2 NCOA3 NCOA6 NCOR2 NDN NFKB1 NPDC1 NRIP1 NSMCE3 PARP1 PHB PKIB PRDM2 PURA RARA RB1 RBL1 RNF126 RNF144A SERTAD2 SETD7 SIRT1 SKP2 SP1 SP2 SP3 SP4 SPIB STAT1 STOML1 TBP TEAD3 TFDP1 TFDP2 TOPBP1 TP53 TP53BP1 TRRAP UBE3A UCHL5 VHL YWHAQ
Entrez ID 7158 1869
HPRD ID 05569 01806
Ensembl ID ENSG00000067369 ENSG00000101412
Uniprot IDs A6NNK5 Q12888 Q01094 Q9BSD8
PDB IDs 1GZH 1KZY 1XNI 2G3R 2IG0 2LVM 2MWO 2MWP 3LGF 3LGL 3LH0 4CRI 4RG2 4X34 5ECG 5J26 5KGF 5Z78 5ZCJ 6CO1 6CO2 6IU7 6IUA 6MXX 6MXY 6MXZ 6MY0 6RML 6RMM 6UPT 6VA5 6VIP 1H24 1O9K 2AZE 5M9N 5M9O 6G0P 6ULS
Enriched GO Terms of Interacting Partners?
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