LNX2 and UBE2Z

  • Number of citations of the paper that reports this interaction (PubMedID 19549727)
  • 74
  • Data Source:
  • BioGRID (two hybrid)

LNX2

UBE2Z

Description ligand of numb-protein X 2 ubiquitin conjugating enzyme E2 Z
Image
GO Annotations Cellular Component
Molecular Function
Biological Process
Pathways
Drugs
Diseases
GWAS
  • Coronary artery disease (myocardial infarction, percutaneous transluminal coronary angioplasty, coronary artery bypass grafting, angina or chromic ischemic heart disease) ( 28714975)
  • Coronary heart disease ( 21378990)
  • Height ( 31562340)
  • Hip circumference adjusted for BMI ( 34021172)
  • Myocardial infarction ( 26343387)
  • Platelet count ( 32888494)
  • Plateletcrit ( 32888494)
  • Type 2 diabetes ( 30054458 29358691)
Interacting Genes 90 interacting genes: ATP5F1B C10orf88 CABP4 CBX4 CCT3 CDK2 CDK4 CDKN2C CRK CXADR DDA1 DRAP1 EAF2 FANCG FHL3 GADD45A GJD2 GLRX3 GRAP2 GRB2 IGSF5 IL16 INMT IP6K2 L3MBTL2 LGALS14 LNX1 LRRC8E MAP2K5 MAPK9 MCM7 MDGA1 MLX MRFAP1L1 MSRB3 MYLIP NAGK NMD3 NOTCH1 NTAQ1 NUDT14 NUMB OPTN PAN3 PARVG PDZRN3 PDZRN4 PEG10 PHYKPL PIK3R1 PIK3R3 PKDREJ POLR1C PPIH PPIL1 PSMD5 PSMF1 PTCD3 RAB6B RBM17 RLIM RNF138 ROPN1 RPA2 SCLY SCNM1 SFN SH3GLB2 SHISA2 SHTN1 SMARCB1 SRSF11 TAB1 TBC1D7 TCL1A TIFA TRAF1 TRAF2 TUBB UBE2D2 UBE2H UBE2I UBE2T UBE2Z USP2 VTN YJU2 ZNF148 ZNF410 ZNF581 39 interacting genes: AK8 BMPR1B CCT3 DZIP3 GORASP2 HLTF HMBOX1 INCA1 LNX2 LPL MDM2 OTUB1 PLEKHA6 PLEKHF2 PPP1CA PRKN RAPSN REL RNF103 RNF130 RNF139 RNF144B RNF150 RNF166 RNF41 RNF5 SMAD1 SMAD4 SRA1 SYVN1 TGFBR1 TRAIP TRIM27 TRIM3 TRIM46 TRIM65 UBA1 UBA6 UBD
Entrez ID 222484 65264
HPRD ID 10042 08589
Ensembl ID ENSG00000139517 ENSG00000159202
Uniprot IDs Q8N448 Q9H832
PDB IDs 2VWR 5DIN 5E11 5E1Y 5E21 5E22 5A4P
Enriched GO Terms of Interacting Partners?
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