LNX2 and MYLIP

  • Number of citations of the paper that reports this interaction (PubMedID 29892012)
  • 25
  • Data Source:
  • BioGRID (two hybrid)

LNX2

MYLIP

Description ligand of numb-protein X 2 myosin regulatory light chain interacting protein
Image
GO Annotations Cellular Component
Molecular Function
Biological Process
Pathways
Drugs
Diseases
GWAS
  • Apolipoprotein B levels ( 32203549)
  • Asthma exacerbations in inhaled corticosteroid treatment ( 30697902)
  • Cholesterol, total ( 24097068)
  • Diisocyanate-induced asthma ( 25918132)
  • Femoral neck bone mineral density ( 30172743)
  • LDL cholesterol ( 24097068 20864672 25961943)
  • LDL cholesterol levels ( 32203549 28334899 30698716)
  • LDL cholesterol levels in current drinkers ( 30698716)
  • LDL cholesterol levels x alcohol consumption (drinkers vs non-drinkers) interaction (2df) ( 30698716)
  • LDL cholesterol levels x alcohol consumption (regular vs non-regular drinkers) interaction (2df) ( 30698716)
  • Major depressive disorder ( 23377640)
  • Medication use (HMG CoA reductase inhibitors) ( 31015401)
  • Response to statins (LDL cholesterol change) ( 22331829)
  • Total cholesterol levels ( 28334899)
Interacting Genes 90 interacting genes: ATP5F1B C10orf88 CABP4 CBX4 CCT3 CDK2 CDK4 CDKN2C CRK CXADR DDA1 DRAP1 EAF2 FANCG FHL3 GADD45A GJD2 GLRX3 GRAP2 GRB2 IGSF5 IL16 INMT IP6K2 L3MBTL2 LGALS14 LNX1 LRRC8E MAP2K5 MAPK9 MCM7 MDGA1 MLX MRFAP1L1 MSRB3 MYLIP NAGK NMD3 NOTCH1 NTAQ1 NUDT14 NUMB OPTN PAN3 PARVG PDZRN3 PDZRN4 PEG10 PHYKPL PIK3R1 PIK3R3 PKDREJ POLR1C PPIH PPIL1 PSMD5 PSMF1 PTCD3 RAB6B RBM17 RLIM RNF138 ROPN1 RPA2 SCLY SCNM1 SFN SH3GLB2 SHISA2 SHTN1 SMARCB1 SRSF11 TAB1 TBC1D7 TCL1A TIFA TRAF1 TRAF2 TUBB UBE2D2 UBE2H UBE2I UBE2T UBE2Z USP2 VTN YJU2 ZNF148 ZNF410 ZNF581 42 interacting genes: ADAMTSL4 AR ARID5A CNPY2 CRK DAPP1 DDIT4L EFHC2 EXOSC5 FAM217B GMCL1 HOOK2 INO80B KANK4 KDM1A LDLR LNX2 LRP8 MIPOL1 MTAP MYL12B NHLRC4 NOXA1 NR1D2 PAX9 RASSF5 SCNM1 SDCBP SRPK2 TCEANC TSC1 TSC22D4 UBE2D2 UBE2D3 UBE2D4 UBE2N VLDLR ZBTB16 ZBTB18 ZBTB42 ZNF417 ZNF438
Entrez ID 222484 29116
HPRD ID 10042 17621
Ensembl ID ENSG00000139517 ENSG00000007944
Uniprot IDs Q8N448 Q5TIA5 Q8WY64
PDB IDs 2VWR 5DIN 5E11 5E1Y 5E21 5E22 2YHN 2YHO 6QLY 6QLZ
Enriched GO Terms of Interacting Partners?
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