S1PR3 and COMT

  • Number of citations of the paper that reports this interaction (PubMedID 32296183)
  • 86
  • Data Source:
  • BioGRID (two hybrid)

S1PR3

COMT

Description sphingosine-1-phosphate receptor 3 catechol-O-methyltransferase
Image No pdb structure
GO Annotations Cellular Component
Molecular Function
Biological Process
Pathways
Drugs
Diseases
GWAS
  • Cardiometabolic and hematological traits ( 27668658)
  • Logical memory (delayed recall) in Alzheimer's disease dementia ( 29274321)
  • Monocyte percentage of white cells ( 32888494 27863252)
  • Response to statins (LDL cholesterol change) ( 22331829)
  • Spleen volume ( 34128465)
  • Systolic blood pressure x smoking status (ever vs never) interaction (2df test) ( 29455858)
  • Blood metabolite levels ( 24816252)
  • Serum metabolite levels ( 23093944)
  • Systolic blood pressure x alcohol consumption interaction (2df test) ( 29912962)
  • Urinary metabolite levels in chronic kidney disease ( 31959995)
  • Urinary metabolite modules (eigenmetabolites) in chronic kidney disease ( 31959995)
Interacting Genes 6 interacting genes: COMT GNA13 GNAI1 GNAQ GYPB HTR1A 74 interacting genes: ACE AQP7 AVPR2 BEST2 BRS3 CCL4L2 CDC27 CDC42 CNR2 CREB3L1 EMD FAM209A FFAR3 FXR2 GET1 GJB1 GJB3 GJB4 GJB5 GLP1R GPR152 GPR161 GPR42 HCK HIBADH HOPX HSD3B7 KCNK5 KRT31 KRT40 KRTAP5-9 LITAF MFSD14B MRPS5 MTNR1A MYADML2 NIPAL4 OTOP3 PGAP2 PLPP6 REEP4 RGS2 RHBDD2 RHBDL1 S1PR3 SELENOK SLC10A6 SLC16A7 SLC2A5 SLC35A4 SLC35F1 SLC39A1 SLC39A2 SLC48A1 SLC7A1 SLC7A8 SMIM1 THSD7A TLCD4 TMEM100 TMEM120B TMEM14B TMEM14C TMEM187 TMEM205 TMEM222 TMEM50A TRHR TRIP13 VAMP3 VAMP5 VKORC1 XRN2 ZNF43
Entrez ID 1903 1312
HPRD ID 03572 00284
Ensembl ID ENSG00000213694 ENSG00000093010
Uniprot IDs Q99500 A0A140VJG8 P21964
PDB IDs 3A7E 3BWM 3BWY 4PYI 4PYJ 4PYK 4XUC 4XUD 4XUE 5LSA 6I3C 6I3D
Enriched GO Terms of Interacting Partners?
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