COMT and KCNK5

  • Number of citations of the paper that reports this interaction (PubMedID 32296183)
  • 86
  • Data Source:
  • BioGRID (two hybrid)

COMT

KCNK5

Description catechol-O-methyltransferase potassium two pore domain channel subfamily K member 5
Image No pdb structure
GO Annotations Cellular Component
Molecular Function
Biological Process
Pathways
Drugs
Diseases
GWAS
  • Blood metabolite levels ( 24816252)
  • Serum metabolite levels ( 23093944)
  • Systolic blood pressure x alcohol consumption interaction (2df test) ( 29912962)
  • Urinary metabolite levels in chronic kidney disease ( 31959995)
  • Urinary metabolite modules (eigenmetabolites) in chronic kidney disease ( 31959995)
Interacting Genes 74 interacting genes: ACE AQP7 AVPR2 BEST2 BRS3 CCL4L2 CDC27 CDC42 CNR2 CREB3L1 EMD FAM209A FFAR3 FXR2 GET1 GJB1 GJB3 GJB4 GJB5 GLP1R GPR152 GPR161 GPR42 HCK HIBADH HOPX HSD3B7 KCNK5 KRT31 KRT40 KRTAP5-9 LITAF MFSD14B MRPS5 MTNR1A MYADML2 NIPAL4 OTOP3 PGAP2 PLPP6 REEP4 RGS2 RHBDD2 RHBDL1 S1PR3 SELENOK SLC10A6 SLC16A7 SLC2A5 SLC35A4 SLC35F1 SLC39A1 SLC39A2 SLC48A1 SLC7A1 SLC7A8 SMIM1 THSD7A TLCD4 TMEM100 TMEM120B TMEM14B TMEM14C TMEM187 TMEM205 TMEM222 TMEM50A TRHR TRIP13 VAMP3 VAMP5 VKORC1 XRN2 ZNF43 30 interacting genes: ADIPOQ AGTRAP APP AQP1 ATP5PF BNIP2 CMTM5 COMT CYB5B FRAT1 GJB2 IGFBP5 LHFPL5 MAN2B2 ORMDL3 SLC66A2 SMCO4 STRIT1 TM4SF4 TMEM128 TMEM14A TMEM176A TMEM218 TMEM54 TMEM60 TNFRSF10C TSPAN33 VAMP3 YIF1A YIPF6
Entrez ID 1312 8645
HPRD ID 00284 04604
Ensembl ID ENSG00000093010 ENSG00000164626
Uniprot IDs A0A140VJG8 P21964 A0A024RD32 A0A0B6VPR3 O95279
PDB IDs 3A7E 3BWM 3BWY 4PYI 4PYJ 4PYK 4XUC 4XUD 4XUE 5LSA 6I3C 6I3D
Enriched GO Terms of Interacting Partners?
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