S1PR3

Description		sphingosine-1-phosphate receptor 3
Image		No pdb structure
GO Annotations	Cellular Component	Extracellular Region Cytoplasm Plasma Membrane Integral Component Of Plasma Membrane
	Molecular Function	G Protein-coupled Receptor Activity Integrin Binding Protein Binding Lipid Binding Sphingosine-1-phosphate Receptor Activity
	Biological Process	Sphingosine-1-phosphate Receptor Signaling Pathway Inflammatory Response G Protein-coupled Receptor Signaling Pathway Adenylate Cyclase-activating G Protein-coupled Receptor Signaling Pathway Adenylate Cyclase-inhibiting G Protein-coupled Receptor Signaling Pathway Positive Regulation Of Cytosolic Calcium Ion Concentration Notch Signaling Pathway Positive Regulation Of Cell Population Proliferation Anatomical Structure Morphogenesis Regulation Of Metabolic Process Regulation Of Interleukin-1 Beta Production Negative Regulation Of Establishment Of Endothelial Barrier
Pathways		G alpha (i) signalling events Lysosphingolipid and LPA receptors Extra-nuclear estrogen signaling
Drugs		Fingolimod
Diseases
GWAS		Cardiometabolic and hematological traits ( 27668658) Logical memory (delayed recall) in Alzheimer's disease dementia ( 29274321) Monocyte percentage of white cells ( 32888494 27863252) Response to statins (LDL cholesterol change) ( 22331829) Spleen volume ( 34128465) Systolic blood pressure x smoking status (ever vs never) interaction (2df test) ( 29455858)
Interacting Genes		6 interacting genes: COMT GNA13 GNAI1 GNAQ GYPB HTR1A
Entrez ID		1903
HPRD ID		03572
Ensembl ID		ENSG00000213694
Uniprot IDs		Q99500
PDB IDs
Enriched GO Terms of Interacting Partners?
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