DRD2 and KCNJ6

  • Number of citations of the paper that reports this interaction (PubMedID 12297500)
  • 49
  • Data Source:
  • HPRD (in vitro, in vivo)

DRD2

KCNJ6

Description dopamine receptor D2 potassium inwardly rectifying channel subfamily J member 6
Image No pdb structure
GO Annotations Cellular Component
Molecular Function
Biological Process
Pathways
Drugs
Diseases
GWAS
  • Alcohol consumption ( 31358974)
  • Alcohol consumption (drinks per week) ( 30643258 30679032)
  • Alcohol consumption (heavy vs. light/non-drinkers) ( 31998841)
  • Alcohol use disorder ( 30940813)
  • Alcohol use disorder (consumption score) ( 33861876)
  • Alcoholic chronic pancreatitis ( 28754779)
  • Anorexia nervosa, attention-deficit/hyperactivity disorder, autism spectrum disorder, bipolar disorder, major depression, obsessive-compulsive disorder, schizophrenia, or Tourette syndrome (pleiotropy) ( 31835028)
  • Anxiety ( 33859377)
  • Autism spectrum disorder or schizophrenia ( 28540026)
  • Bipolar disorder ( 33263727)
  • Body mass index ( 26426971)
  • Chronotype ( 30696823)
  • Cognitive ability, years of educational attainment or schizophrenia (pleiotropy) ( 31374203)
  • Depression ( 33859377)
  • General factor of neuroticism ( 30867560)
  • Inferior temporal gyrus volume ( 31530798)
  • Information processing speed ( 25869804)
  • Interferon alpha levels in systemic lupus erythematosus ( 25338677)
  • Mood instability ( 31168069)
  • Neuroticism ( 27089181 29255261)
  • Problematic alcohol use ( 32451486)
  • Response to antipsychotic treatment in schizophrenia (working memory) ( 21107309)
  • Schizophrenia ( 28991256 25056061 29483656 30285260)
  • Select biomarker traits ( 17903293)
  • Sleep duration ( 27992416)
  • Smoking cessation ( 33082346)
  • Smoking status (current vs mixed) ( 33082346)
  • Smoking status (current vs never) ( 33082346)
  • Sociability score ( 34054130)
  • Systolic blood pressure in sickle cell anemia ( 24058526)
  • Triglycerides ( 30275531)
  • Walking pace ( 33128006)
  • Worry too long after an embarrassing experience ( 34054130)
  • Body size at age 10 ( 32376654)
  • Clostridioides difficle infection ( 33841421)
  • Electroencephalographic traits in alcoholism ( 22554406)
  • Response to placebo treatment in childhood asthma (FVC change) ( 31557306)
  • Rosacea symptom severity ( 29771307)
Interacting Genes 99 interacting genes: ABCA2 ADGRB1 ADGRG1 ADORA2A APH1A ARL1 ARL6IP6 ATP6V0A2 ATP6V0C BCAP29 BCAP31 CADPS CADPS2 CALM1 CALM3 CASP1 CCKBR CCNA2 CD3E CD3G CERS1 CERS2 CHPT1 CLDND1 CLIC6 CRELD1 E2F6 EPB41 EPB41L1 FLNA GABBR1 GABBR2 GDPD2 GHITM GIPC1 GNAI2 GNAI3 GNAZ GNB5 GPC6 GPR137 GPR37 GRIA2 GRINA HRH3 IL10RA INPPL1 KBTBD6 KBTBD7 KCNJ6 KCNJ9 LPAR1 NCS1 NDUFV1 NEFM NQO2 NSF OPRM1 PAQR6 PAWR PIGG PLLP PLPPR3 PPP1R9B PSG7 RBM22 RHBDD2 RTN1 RTN3 RTN4 SERINC3 SGSH SLC15A4 SLC22A17 SLC35B1 SLC4A3 SLC6A1 SLC6A3 SMIM7 SPP1 SSTR2 SSTR5 SYNGR2 TF TMEFF2 TMEM101 TMEM11 TMEM63A TRAM1 TRPC4 TRPC5 TSPAN3 TSPAN7 TTYH1 VWA5A WFS1 WLS YIPF3 ZDHHC4 64 interacting genes: ADRB2 AIG1 APOD BCL2L2 BET1 BIRC5 C14orf180 CMTM5 CNPY3 COL4A5 DLG1 DRD2 EDDM3B ERG28 FAM20B FIS1 FUNDC2 FXYD6 GABBR1 HMOX2 ICMT ITGAM KCNJ3 KCNJ9 LEPROTL1 LPAR3 LPCAT2 MIP MYO15B NINJ2 ORMDL2 PEX11G PEX16 PLLP PMP22 PNLIPRP1 RPRM RPS6KA2 RTP2 SCAMP4 SCARF1 SCD SERTM1 STATH STRIT1 SYT3 THSD7B TM6SF2 TMEM107 TMEM120B TMEM203 TMEM208 TMEM218 TMPPE TNFRSF10C TSPO2 UBIAD1 UNC50 UPK1B VSTM1 XIAP YIPF1 YIPF6 ZDHHC24
Entrez ID 1813 3763
HPRD ID 00539 02929
Ensembl ID ENSG00000149295 ENSG00000157542
Uniprot IDs A0A024R3C5 A0A024R3I6 P14416 P48051
PDB IDs 1I15 5AER 6CM4 6LUQ 6VMS 7JVR
Enriched GO Terms of Interacting Partners?
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Tagcloud (Difference) ?
Tagcloud (Intersection) ?