KCNJ6 and LPCAT2

Number of citations of the paper that reports this interaction (PubMedID 32296183)
86

Data Source:
BioGRID (two hybrid)

		KCNJ6	LPCAT2
Description		potassium inwardly rectifying channel subfamily J member 6	lysophosphatidylcholine acyltransferase 2
Image		No pdb structure	No pdb structure
GO Annotations	Cellular Component	Golgi Apparatus Plasma Membrane Voltage-gated Potassium Channel Complex	Golgi Membrane Endoplasmic Reticulum Endoplasmic Reticulum Membrane Golgi Stack Lipid Droplet Plasma Membrane Integral Component Of Membrane
	Molecular Function	Inward Rectifier Potassium Channel Activity Protein Binding G-protein Activated Inward Rectifier Potassium Channel Activity	1-acylglycerol-3-phosphate O-acyltransferase Activity Calcium Ion Binding Protein Binding 2-acylglycerol-3-phosphate O-acyltransferase Activity 1-alkenylglycerophosphocholine O-acyltransferase Activity 1-acylglycerophosphocholine O-acyltransferase Activity 1-alkylglycerophosphocholine O-acetyltransferase Activity Plasmalogen Synthase Activity
	Biological Process	Potassium Ion Transport Regulation Of Ion Transmembrane Transport Potassium Ion Import Across Plasma Membrane	Platelet Activating Factor Biosynthetic Process Phosphatidylcholine Acyl-chain Remodeling Membrane Organization
Pathways		Activation of G protein gated Potassium channels Inhibition of voltage gated Ca2+ channels via Gbeta/gamma subunits	Acyl chain remodelling of PC
Drugs		Ethanol Halothane Ifenprodil Isavuconazole
Diseases
GWAS		Body size at age 10 ( 32376654) Clostridioides difficle infection ( 33841421) Electroencephalographic traits in alcoholism ( 22554406) Response to placebo treatment in childhood asthma (FVC change) ( 31557306) Rosacea symptom severity ( 29771307)	Angiotensin-converting enzyme inhibitor intolerance ( 28030426) Thyroid hormone levels ( 23408906)
Interacting Genes		64 interacting genes: ADRB2 AIG1 APOD BCL2L2 BET1 BIRC5 C14orf180 CMTM5 CNPY3 COL4A5 DLG1 DRD2 EDDM3B ERG28 FAM20B FIS1 FUNDC2 FXYD6 GABBR1 HMOX2 ICMT ITGAM KCNJ3 KCNJ9 LEPROTL1 LPAR3 LPCAT2 MIP MYO15B NINJ2 ORMDL2 PEX11G PEX16 PLLP PMP22 PNLIPRP1 RPRM RPS6KA2 RTP2 SCAMP4 SCARF1 SCD SERTM1 STATH STRIT1 SYT3 THSD7B TM6SF2 TMEM107 TMEM120B TMEM203 TMEM208 TMEM218 TMPPE TNFRSF10C TSPO2 UBIAD1 UNC50 UPK1B VSTM1 XIAP YIPF1 YIPF6 ZDHHC24	8 interacting genes: CREB3 EBP ERGIC3 HSD17B13 KCNJ6 MFSD14B RETREG3 RHBDD1
Entrez ID		3763	54947
HPRD ID		02929	07913
Ensembl ID		ENSG00000157542	ENSG00000087253
Uniprot IDs		P48051	Q7L5N7
PDB IDs
Enriched GO Terms of Interacting Partners?
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