DIO1 and CD48

		DIO1	CD48
Description		iodothyronine deiodinase 1	CD48 molecule
Image		No pdb structure
GO Annotations	Cellular Component	Endoplasmic Reticulum Membrane Plasma Membrane Integral Component Of Membrane	Plasma Membrane External Side Of Plasma Membrane Membrane Anchored Component Of Membrane Intrinsic Component Of Plasma Membrane Membrane Raft Extracellular Exosome
	Molecular Function	Thyroxine 5'-deiodinase Activity Selenium Binding	Antigen Binding Protein Binding Signaling Receptor Activity
	Biological Process	Cellular Amino Acid Metabolic Process Thyroid Hormone Generation Thyroid Hormone Metabolic Process Hormone Biosynthetic Process	Regulation Of Adaptive Immune Response Defense Response T Cell Activation
Pathways		Regulation of thyroid hormone activity	Cell surface interactions at the vascular wall
Drugs
Diseases
GWAS		Free thyroxine concentration ( 25743335) Serum metabolite concentrations in chronic kidney disease ( 33838163) Thyroid hormone levels ( 23408906)	Blood protein levels ( 30072576 29875488) Inflammatory bowel disease ( 23128233) Itch intensity from mosquito bite ( 28199695) Multiple sclerosis ( 31604244) Venous thromboembolism adjusted for sickle cell variant rs77121243-T ( 28203683)
Interacting Genes		2 interacting genes: ARTN CD48	20 interacting genes: ACKR1 BRIX1 C1orf68 CD2 CD244 CD247 DIO1 E2F2 EEF1D EFNA1 EFNA3 FYN GNAI3 IL18R1 IL18RAP LCK LY9 MAST2 OAZ3 P4HA1
Entrez ID		1733	962
HPRD ID		01002	00177
Ensembl ID		ENSG00000211452	ENSG00000117091
Uniprot IDs		A8K415 P49895	A0A087X1S7 P09326
PDB IDs			2EDO
Enriched GO Terms of Interacting Partners?
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