CLEC14A and CYB561D2

Number of citations of the paper that reports this interaction (PubMedID 32296183)
86

Data Source:
BioGRID (two hybrid)

		CLEC14A	CYB561D2
Description		C-type lectin domain containing 14A	cytochrome b561 family member D2
Image		No pdb structure	No pdb structure
GO Annotations	Cellular Component	External Side Of Plasma Membrane Integral Component Of Membrane Collagen-containing Extracellular Matrix	Endoplasmic Reticulum Endoplasmic Reticulum Membrane Integral Component Of Membrane Cytoplasmic Vesicle Membrane Vesicle
	Molecular Function	Protein Binding Carbohydrate Binding Extracellular Matrix Binding Extracellular Matrix Protein Binding	Protein Binding Oxidoreductase Activity Heme Binding Metal Ion Binding Transmembrane Ascorbate Ferrireductase Activity Transmembrane Monodehydroascorbate Reductase Activity
	Biological Process	Lymphangiogenesis Cell Migration Involved In Sprouting Angiogenesis Cell Migration Vascular Endothelial Growth Factor Receptor-2 Signaling Pathway Vascular Endothelial Growth Factor Receptor-3 Signaling Pathway	Transmembrane Transport Ascorbate Homeostasis
Pathways
Drugs		Resveratrol
Diseases
GWAS		Metabolite levels (5-HIAA/ MHPG Ratio) ( 23319000) Two-hour glucose ( 34059833) Type 2 diabetes ( 30297969 32499647) Type 2 diabetes (age of onset) ( 28060188)	Brain morphology (min-P) ( 32665545) Brain morphology (MOSTest) ( 32665545) Cortical surface area (MOSTest) ( 32665545) Depressive symptom (appetite changes) (binary trait) ( 31530331) Depressive symptoms (binary sum-score) ( 31530331) Depressive symptoms (sum-score) ( 31530331) Sleep duration (short sleep) ( 30846698) Subcortical volume (min-P) ( 32665545) Subcortical volume (MOSTest) ( 32665545)
Interacting Genes		13 interacting genes: ATP6V0C CLDN19 CLDN4 CYB561D2 EMD LHFPL5 MALL MGST2 MS4A1 PMP22 TMEM243 TSPAN2 VAMP3	22 interacting genes: APP ARL13B CD79A CLDN7 CLEC14A CLNK COQ9 CREB3L1 ERGIC3 FAM209A GPX8 LMNA PDE4A PGRMC2 PSCA PTPN5 RMDN3 SLC18A1 SLC30A2 TMEM154 TMEM45B UNC119
Entrez ID		161198	11068
HPRD ID		10711	06143
Ensembl ID		ENSG00000176435	ENSG00000114395
Uniprot IDs		Q86T13	A0A024R342 O14569
PDB IDs
Enriched GO Terms of Interacting Partners?
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