CYB561D2 and CLEC14A

Number of citations of the paper that reports this interaction (PubMedID 32296183)
86

Data Source:
BioGRID (two hybrid)

		CYB561D2	CLEC14A
Description		cytochrome b561 family member D2	C-type lectin domain containing 14A
Image		No pdb structure	No pdb structure
GO Annotations	Cellular Component	Endoplasmic Reticulum Endoplasmic Reticulum Membrane Integral Component Of Membrane Cytoplasmic Vesicle Membrane Vesicle	External Side Of Plasma Membrane Integral Component Of Membrane Collagen-containing Extracellular Matrix
	Molecular Function	Protein Binding Oxidoreductase Activity Heme Binding Metal Ion Binding Transmembrane Ascorbate Ferrireductase Activity Transmembrane Monodehydroascorbate Reductase Activity	Protein Binding Carbohydrate Binding Extracellular Matrix Binding Extracellular Matrix Protein Binding
	Biological Process	Transmembrane Transport Ascorbate Homeostasis	Lymphangiogenesis Cell Migration Involved In Sprouting Angiogenesis Cell Migration Vascular Endothelial Growth Factor Receptor-2 Signaling Pathway Vascular Endothelial Growth Factor Receptor-3 Signaling Pathway
Pathways
Drugs			Resveratrol
Diseases
GWAS		Brain morphology (min-P) ( 32665545) Brain morphology (MOSTest) ( 32665545) Cortical surface area (MOSTest) ( 32665545) Depressive symptom (appetite changes) (binary trait) ( 31530331) Depressive symptoms (binary sum-score) ( 31530331) Depressive symptoms (sum-score) ( 31530331) Sleep duration (short sleep) ( 30846698) Subcortical volume (min-P) ( 32665545) Subcortical volume (MOSTest) ( 32665545)	Metabolite levels (5-HIAA/ MHPG Ratio) ( 23319000) Two-hour glucose ( 34059833) Type 2 diabetes ( 30297969 32499647) Type 2 diabetes (age of onset) ( 28060188)
Interacting Genes		22 interacting genes: APP ARL13B CD79A CLDN7 CLEC14A CLNK COQ9 CREB3L1 ERGIC3 FAM209A GPX8 LMNA PDE4A PGRMC2 PSCA PTPN5 RMDN3 SLC18A1 SLC30A2 TMEM154 TMEM45B UNC119	13 interacting genes: ATP6V0C CLDN19 CLDN4 CYB561D2 EMD LHFPL5 MALL MGST2 MS4A1 PMP22 TMEM243 TSPAN2 VAMP3
Entrez ID		11068	161198
HPRD ID		06143	10711
Ensembl ID		ENSG00000114395	ENSG00000176435
Uniprot IDs		A0A024R342 O14569	Q86T13
PDB IDs
Enriched GO Terms of Interacting Partners?
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