COX5B and NPHP1

		COX5B	NPHP1
Description		cytochrome c oxidase subunit 5B	nephrocystin 1
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GO Annotations	Cellular Component	Mitochondrion Mitochondrial Inner Membrane Mitochondrial Respiratory Chain Complex IV	Cytoplasm Cytosol Cytoskeleton Cell-cell Junction Adherens Junction Bicellular Tight Junction Cilium Membrane Motile Cilium Photoreceptor Connecting Cilium
	Molecular Function	Cytochrome-c Oxidase Activity Protein Binding Metal Ion Binding	Structural Molecule Activity Protein Binding
	Biological Process	Mitochondrial Electron Transport, Cytochrome C To Oxygen Respiratory Gaseous Exchange By Respiratory System Proton Transmembrane Transport	Signal Transduction Excretion Visual Behavior Cell Projection Organization Actin Cytoskeleton Organization Spermatid Differentiation Retina Development In Camera-type Eye Protein Localization Involved In Establishment Of Planar Polarity Cell-cell Adhesion Positive Regulation Of Bicellular Tight Junction Assembly
Pathways		TP53 Regulates Metabolic Genes Respiratory electron transport Cytoprotection by HMOX1	Anchoring of the basal body to the plasma membrane
Drugs		Cholic Acid N-Formylmethionine
Diseases
GWAS		Bipolar disorder ( 31043756) Brain morphology (min-P) ( 32665545) Brain morphology (MOSTest) ( 32665545) Cortical surface area (min-P) ( 32665545) Cortical surface area (MOSTest) ( 32665545) Cortical thickness (MOSTest) ( 32665545) Subcortical volume (min-P) ( 32665545) Subcortical volume (MOSTest) ( 32665545)
Interacting Genes		36 interacting genes: AR ARID5A BHLHE40 CDC42EP2 CDR2 CDR2L DOK3 FAM228A FLOT1 GOLGA2 IHO1 KRT15 KRT27 KRT31 KRT33B LSM4 MCCD1 MID2 NPHP1 NUDT5 OIP5 PLEKHF2 PNMA1 PPP1R32 PRDM6 PRKAR1B PRR22 RBM48 SLAIN1 TASOR2 TEX12 TFIP11 TRAF1 TRIM23 TRIM27 VPS28	18 interacting genes: ADAM15 ARHGAP32 BCAR1 BCL2L11 COX5B FBXO7 FLNA FLNB FLNC INVS KHDRBS1 NPHP3 NPHP4 PAK2 PTK2B TNK2 TUBB UBQLN4
Entrez ID		1329	4867
HPRD ID		00467	09524
Ensembl ID		ENSG00000135940	ENSG00000144061
Uniprot IDs		A0A384NL93 P10606	C9JNM7 O15259
PDB IDs		5Z62	1S1N 6O1Q
Enriched GO Terms of Interacting Partners?
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