NPHP1 and FLNC

Number of citations of the paper that reports this interaction (PubMedID 12006559)
21

Data Source:
HPRD (in vitro, in vivo, two hybrid)

		NPHP1	FLNC
Description		nephrocystin 1	filamin C
Image
GO Annotations	Cellular Component	Cytoplasm Cytosol Cytoskeleton Cell-cell Junction Adherens Junction Bicellular Tight Junction Cilium Membrane Motile Cilium Photoreceptor Connecting Cilium	Cytoplasm Cytosol Cytoskeleton Plasma Membrane Focal Adhesion Sarcoplasm Z Disc Sarcolemma Costamere
	Molecular Function	Structural Molecule Activity Protein Binding	Protein Binding Cytoskeletal Protein Binding Ankyrin Binding Actin Filament Binding
	Biological Process	Signal Transduction Excretion Visual Behavior Cell Projection Organization Actin Cytoskeleton Organization Spermatid Differentiation Retina Development In Camera-type Eye Protein Localization Involved In Establishment Of Planar Polarity Cell-cell Adhesion Positive Regulation Of Bicellular Tight Junction Assembly	Actin Cytoskeleton Organization Muscle Cell Development
Pathways		Anchoring of the basal body to the plasma membrane	Cell-extracellular matrix interactions
Drugs
Diseases
GWAS			Dilated cardiomyopathy ( 33495596) Dilated cardiomyopathy (MTAG) ( 33495596) Hypertrophic cardiomyopathy (sarcomere positive) ( 33495597) Reading disability or specific language impairment (pleiotropy) ( 25065397) Reading disability or specific language impairment adjusted for intelligence quotient (pleiotropy) ( 25065397)
Interacting Genes		18 interacting genes: ADAM15 ARHGAP32 BCAR1 BCL2L11 COX5B FBXO7 FLNA FLNB FLNC INVS KHDRBS1 NPHP3 NPHP4 PAK2 PTK2B TNK2 TUBB UBQLN4	35 interacting genes: ADRA1A ADRA1B ADRA1D CAPN3 CDC42 ENO1 FURIN HIPK3 HSPB2 INPPL1 KCND2 KY MAP2K4 MTDH MYBPC2 MYOT MYOZ1 MYOZ2 MYOZ3 NPHP1 PHLDB2 PRKAB2 PRKCA REPS1 RPS6KA2 SGCD SGCG SYNPO2 TRIM54 TRIM55 TRIM63 USP25 WNK1 XIRP1 XIRP2
Entrez ID		4867	2318
HPRD ID		09524	00018
Ensembl ID		ENSG00000144061	ENSG00000128591
Uniprot IDs		C9JNM7 O15259	Q14315 Q59H94
PDB IDs		1S1N 6O1Q	1V05 2D7M 2D7N 2D7O 2D7P 2D7Q 2K9U 2NQC 3V8O 4MGX
Enriched GO Terms of Interacting Partners?
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