COX5B and PRKAR1B

Number of citations of the paper that reports this interaction (PubMedID 32296183)
86

Data Source:
BioGRID (two hybrid)

		COX5B	PRKAR1B
Description		cytochrome c oxidase subunit 5B	protein kinase cAMP-dependent type I regulatory subunit beta
Image
GO Annotations	Cellular Component	Mitochondrion Mitochondrial Inner Membrane Mitochondrial Respiratory Chain Complex IV	Cytoplasm Multivesicular Body Cytosol Plasma Membrane CAMP-dependent Protein Kinase Complex Ciliary Base Schaffer Collateral - CA1 Synapse Hippocampal Mossy Fiber To CA3 Synapse Glutamatergic Synapse
	Molecular Function	Cytochrome-c Oxidase Activity Protein Binding Metal Ion Binding	CAMP-dependent Protein Kinase Inhibitor Activity Protein Binding CAMP-dependent Protein Kinase Regulator Activity CAMP Binding Protein Kinase A Catalytic Subunit Binding
	Biological Process	Mitochondrial Electron Transport, Cytochrome C To Oxygen Respiratory Gaseous Exchange By Respiratory System Proton Transmembrane Transport	Protein Phosphorylation Learning Or Memory Modulation Of Chemical Synaptic Transmission Regulation Of Synaptic Vesicle Cycle Negative Regulation Of CAMP-dependent Protein Kinase Activity
Pathways		TP53 Regulates Metabolic Genes Respiratory electron transport Cytoprotection by HMOX1	PKA activation PKA activation in glucagon signalling DARPP-32 events Glucagon-like Peptide-1 (GLP1) regulates insulin secretion Vasopressin regulates renal water homeostasis via Aquaporins CREB1 phosphorylation through the activation of Adenylate Cyclase Hedgehog 'off' state ADORA2B mediated anti-inflammatory cytokines production FCGR3A-mediated IL10 synthesis Factors involved in megakaryocyte development and platelet production
Drugs		Cholic Acid N-Formylmethionine
Diseases
GWAS		Bipolar disorder ( 31043756) Brain morphology (min-P) ( 32665545) Brain morphology (MOSTest) ( 32665545) Cortical surface area (min-P) ( 32665545) Cortical surface area (MOSTest) ( 32665545) Cortical thickness (MOSTest) ( 32665545) Subcortical volume (min-P) ( 32665545) Subcortical volume (MOSTest) ( 32665545)	Body size at age 10 ( 32376654) Hematocrit ( 32888494 27863252) Hemoglobin ( 32888494) Hemoglobin concentration ( 27863252) Plasma free amino acid levels ( 30659259) Red blood cell count ( 32888494 27863252)
Interacting Genes		36 interacting genes: AR ARID5A BHLHE40 CDC42EP2 CDR2 CDR2L DOK3 FAM228A FLOT1 GOLGA2 IHO1 KRT15 KRT27 KRT31 KRT33B LSM4 MCCD1 MID2 NPHP1 NUDT5 OIP5 PLEKHF2 PNMA1 PPP1R32 PRDM6 PRKAR1B PRR22 RBM48 SLAIN1 TASOR2 TEX12 TFIP11 TRAF1 TRIM23 TRIM27 VPS28	77 interacting genes: AKAP1 AKAP14 AKAP7 ANKS1A BAG3 BAG6 BOD1L2 CAMSAP1 CBX8 CCDC103 CCDC187 CDC37 CDKN1A CEP19 COX5B DACH1 DTNB EEF2KMT EGFR FAM161A FAM90A1 FCHSD2 GAS2L2 GLIS2 GNL3L GOLGA1 GPKOW GUCA1A IGFN1 INPP5J KANK2 KIF5B L3MBTL2 LENG1 LNX1 MAD1L1 MBD3 MED8 MYO15B NTAQ1 NXF1 PIK3R3 POLE4 PPP1R9A PRKAA2 PRKACA PRKAR1A PRPF18 PSMG1 QRICH1 RARG RUNX1T1 SAP30BP SH2D4A SHC3 SMAD3 SMAD4 SMG9 SNW1 STK16 SYTL4 TASOR2 TEAD4 THRA TSGA10IP UACA VEZF1 WNK1 WRN ZBTB16 ZMYND19 ZNF177 ZNF329 ZNF35 ZNF410 ZNF559-ZNF177 ZNF76
Entrez ID		1329	5575
HPRD ID		00467	01485
Ensembl ID		ENSG00000135940	ENSG00000188191
Uniprot IDs		A0A384NL93 P10606	P31321
PDB IDs		5Z62	4DIN 4F9K
Enriched GO Terms of Interacting Partners?
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