COX5B and FLOT1

Number of citations of the paper that reports this interaction (PubMedID 32296183)
86

Data Source:
BioGRID (two hybrid)

		COX5B	FLOT1
Description		cytochrome c oxidase subunit 5B	flotillin 1
Image			No pdb structure
GO Annotations	Cellular Component	Mitochondrion Mitochondrial Inner Membrane Mitochondrial Respiratory Chain Complex IV	Uropod Lysosomal Membrane Endosome Early Endosome Microtubule Organizing Center Plasma Membrane Caveola Cell-cell Junction Adherens Junction Focal Adhesion External Side Of Plasma Membrane Membrane Basolateral Plasma Membrane Apical Plasma Membrane Flotillin Complex Lamellipodium Cortical Actin Cytoskeleton Cytoplasmic Vesicle Centriolar Satellite Sarcolemma Melanosome Cell-cell Contact Zone Membrane Raft Presynaptic Active Zone Extracellular Exosome Dopaminergic Synapse Glutamatergic Synapse GABA-ergic Synapse
	Molecular Function	Cytochrome-c Oxidase Activity Protein Binding Metal Ion Binding	Protease Binding Protein Binding Ionotropic Glutamate Receptor Binding
	Biological Process	Mitochondrial Electron Transport, Cytochrome C To Oxygen Respiratory Gaseous Exchange By Respiratory System Proton Transmembrane Transport	Membrane Raft Assembly Positive Regulation Of Cytokine Production Positive Regulation Of Protein Phosphorylation Regulation Of Receptor Internalization Axonogenesis Extracellular Matrix Disassembly Positive Regulation Of Protein Binding Positive Regulation Of Synaptic Transmission, Dopaminergic Positive Regulation Of Interferon-beta Production DsRNA Transport Positive Regulation Of Heterotypic Cell-cell Adhesion Positive Regulation Of Toll-like Receptor 3 Signaling Pathway Regulation Of Toll-like Receptor 4 Signaling Pathway Response To Endoplasmic Reticulum Stress Regulation Of Rho Protein Signal Transduction Plasma Membrane Raft Assembly Positive Regulation Of Endocytosis Positive Regulation Of Skeletal Muscle Tissue Development Protein Stabilization Positive Regulation Of NF-kappaB Transcription Factor Activity Regulation Of Neurotransmitter Uptake Positive Regulation Of Cell Adhesion Molecule Production Protein Kinase C Signaling Cellular Response To Exogenous DsRNA Protein Localization To Plasma Membrane Positive Regulation Of Myoblast Fusion Positive Regulation Of Cell Junction Assembly Protein Localization To Membrane Raft Positive Regulation Of Cell-cell Adhesion Mediated By Cadherin
Pathways		TP53 Regulates Metabolic Genes Respiratory electron transport Cytoprotection by HMOX1	RIPK1-mediated regulated necrosis Regulation of necroptotic cell death Synaptic adhesion-like molecules RHOA GTPase cycle RHOB GTPase cycle RHOC GTPase cycle
Drugs		Cholic Acid N-Formylmethionine
Diseases
GWAS		Bipolar disorder ( 31043756) Brain morphology (min-P) ( 32665545) Brain morphology (MOSTest) ( 32665545) Cortical surface area (min-P) ( 32665545) Cortical surface area (MOSTest) ( 32665545) Cortical thickness (MOSTest) ( 32665545) Subcortical volume (min-P) ( 32665545) Subcortical volume (MOSTest) ( 32665545)	Autism spectrum disorder or schizophrenia ( 28540026) Blood protein levels ( 28240269) Cutaneous lupus erythematosus ( 25827949) Decreased fine motor function in Charcot-Marie-Tooth disease 1A (eating with utensils) ( 30958311) General cognitive ability ( 29844566) Handedness (non-right-handed vs right-handed) ( 31504236) Hip circumference adjusted for BMI ( 34021172) Schizophrenia ( 30285260) Sleep duration ( 25469926) Ulcerative colitis ( 20848476)
Interacting Genes		36 interacting genes: AR ARID5A BHLHE40 CDC42EP2 CDR2 CDR2L DOK3 FAM228A FLOT1 GOLGA2 IHO1 KRT15 KRT27 KRT31 KRT33B LSM4 MCCD1 MID2 NPHP1 NUDT5 OIP5 PLEKHF2 PNMA1 PPP1R32 PRDM6 PRKAR1B PRR22 RBM48 SLAIN1 TASOR2 TEX12 TFIP11 TRAF1 TRIM23 TRIM27 VPS28	24 interacting genes: APP ARG1 AURKB BANP CAPN10 CBL CCDC102B COX5B FAM90A1 FLOT2 FYN GOLM1 HGS INCENP NGB NME7 PSMD4 SDHB SHBG SORBS1 SORBS2 SORBS3 SRPK1 UBC
Entrez ID		1329	10211
HPRD ID		00467	06105
Ensembl ID		ENSG00000135940	ENSG00000137312
Uniprot IDs		A0A384NL93 P10606	O75955 Q5ST80
PDB IDs		5Z62
Enriched GO Terms of Interacting Partners?
Tagcloud ?
Tagcloud (Difference) ?
Tagcloud (Intersection) ?