NECAB1 and ATOX1

Number of citations of the paper that reports this interaction (PubMedID 32296183)
86

Data Source:
BioGRID (two hybrid)

		NECAB1	ATOX1
Description		N-terminal EF-hand calcium binding protein 1	antioxidant 1 copper chaperone
Image		No pdb structure
GO Annotations	Cellular Component	Nucleoplasm Cytoplasm Cytosol	Cytosol
	Molecular Function	Molecular_function Calcium Ion Binding Protein Binding Identical Protein Binding	Copper Ion Binding Protein Binding Metallochaperone Activity Copper Chaperone Activity Copper-dependent Protein Binding ATPase Binding Cuprous Ion Binding
	Biological Process	Blastocyst Hatching Biological_process Regulation Of Amyloid Precursor Protein Biosynthetic Process	Copper Ion Transport Negative Regulation Of Apoptotic Process Copper Ion Export
Pathways			Detoxification of Reactive Oxygen Species Ion influx/efflux at host-pathogen interface
Drugs			Cisplatin Sucrose Benzamidine
Diseases
GWAS		Age at first sexual intercourse ( 34211149)	Creatinine levels ( 29403010) Glomerular filtration rate ( 29403010) Red cell distribution width ( 32888494) Systolic blood pressure change trajectory ( 27980656)
Interacting Genes		19 interacting genes: AP1M1 APP ATOX1 BHLHA9 BRPF1 CDC37 CPNE4 CPNE7 CPNE8 DAPK1 DISC1 FMNL2 LNX1 MORF4L1 NECAB2 PAX4 SNX11 TCEA2 TCEANC	9 interacting genes: ATP7A ATP7B CFAP410 COMP FAM118A FKBP4 GGPS1 NECAB1 TRAF4
Entrez ID		64168	475
HPRD ID		16851	03779
Ensembl ID		ENSG00000123119	ENSG00000177556
Uniprot IDs		Q8N987	O00244
PDB IDs			1FE0 1FE4 1FEE 1TL4 1TL5 2K1R 2LQ9 3CJK 3IWL 3IWX 4QOT 4YDX 4YEA 5F0W 5T7L
Enriched GO Terms of Interacting Partners?
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