AHNAK2 and ASGR1

Number of citations of the paper that reports this interaction (PubMedID 32296183)
86

Data Source:
BioGRID (two hybrid)

		AHNAK2	ASGR1
Description		AHNAK nucleoprotein 2	asialoglycoprotein receptor 1
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GO Annotations	Cellular Component	Nucleus Cytoplasm Cytosol Plasma Membrane T-tubule Sarcolemma	Extracellular Region Plasma Membrane Integral Component Of Plasma Membrane
	Molecular Function	Protein Binding	Asialoglycoprotein Receptor Activity Protein Binding Carbohydrate Binding Identical Protein Binding Metal Ion Binding
	Biological Process	Regulation Of RNA Splicing	Receptor-mediated Endocytosis Cellular Response To Extracellular Stimulus
Pathways			Asparagine N-linked glycosylation
Drugs
Diseases
GWAS		Cerebrospinal fluid t-tau levels ( 29274321) Cerebrospinal fluid t-tau levels in normal cognition ( 29274321) Rheumatoid arthritis ( 30423114 24390342) Systemic lupus erythematosus ( 33272962 26663301)	Apolipoprotein B levels ( 32203549) Iron status biomarkers (ferritin levels) ( 33536631) LDL cholesterol levels ( 32203549) Liver enzyme levels (alkaline phosphatase) ( 33972514 22001757) Low density lipoprotein cholesterol levels ( 32154731 33339817) Medication use (HMG CoA reductase inhibitors) ( 31015401) Serum alkaline phosphatase levels ( 33547301 31666285 29403010 33339817) Total cholesterol levels ( 33339817)
Interacting Genes		18 interacting genes: ABLIM2 ASGR1 C3orf52 COA8 CTSA CYB5B CYBC1 FAM3C GABARAPL1 GABARAPL2 IGFBP5 PRAP1 SUMO2 TRMT61A TSPO2 UBIAD1 VAMP3 ZFPL1	44 interacting genes: AHNAK2 AMIGO1 APH1A APP ASGR2 ATP1B4 BLCAP CERS2 CLDN7 CLEC4G CPLX4 CREB3L1 CYB5R3 DHFR ERGIC3 FAM209A FCGR1A FNDC9 GPX8 HIBADH HIVEP1 HSP90AA1 HSP90B1 IGFBP5 KIR2DL3 LAMTOR5 LEUTX LMNA MCEMP1 NEMP1 NLK PDZK1IP1 PLS3 RBBP6 RNF19B SAR1A SLC10A1 SLC35C2 SPAG4 SUSD3 TG TMX2 VKORC1 VSIR
Entrez ID		113146	432
HPRD ID		12261	00151
Ensembl ID		ENSG00000185567	ENSG00000141505
Uniprot IDs		Q8IVF2	P07306 Q6FGQ5
PDB IDs		4CN0	1DV8 5JPV 5JQ1 6YAU
Enriched GO Terms of Interacting Partners?
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