KLHL2 and NAP1L2

Number of citations of the paper that reports this interaction (PubMedID 32296183)
86

		KLHL2	NAP1L2
Description		kelch like family member 2	nucleosome assembly protein 1 like 2
Image			No pdb structure
GO Annotations	Cellular Component	Ruffle Cytoplasm Cytosol Actin Cytoskeleton Lamellipodium Cul3-RING Ubiquitin Ligase Complex	Chromatin Nucleus
	Molecular Function	Actin Binding Protein Binding Identical Protein Binding	Chromatin Binding Protein Binding Histone Binding
	Biological Process	Protein Ubiquitination	Nucleosome Assembly Positive Regulation Of Neuron Differentiation Positive Regulation Of Histone H3-K14 Acetylation Regulation Of Stem Cell Division Positive Regulation Of Histone H3-K9 Acetylation
Pathways		Neddylation Antigen processing: Ubiquitination & Proteasome degradation
Drugs
Diseases
GWAS		Cognitive function ( 24684796) General cognitive ability ( 29844566) Neuroticism ( 27067015)	Bipolar disorder ( 31043756)
Interacting Genes		32 interacting genes: ACTC1 BCAM BYSL C20orf85 CCDC43 CDC37 CLK2 CUL3 CWC22 ELOA FRAS1 KEAP1 KLHL12 KLHL3 MFAP1 NAP1L2 NTAQ1 PADI6 PIBF1 POLR3C SDCBP TMA16 TNPO2 TRIM50 TXNDC12 UBE2C UBE2D1 UBE2I UCK1 WNK1 WNK4 ZNF114	14 interacting genes: CCDC146 CCDC185 DMAP1 FAM81A KLHL2 MED30 NAP1L1 NAP1L5 POFUT1 PPP1R13B PPP3R1 SCNM1 SH3BP5 SP110
Entrez ID		11275	4674
HPRD ID		09311	02066
Ensembl ID		ENSG00000109466	ENSG00000186462
Uniprot IDs		B4DFZ5 E9PEX9 O95198	Q9ULW6
PDB IDs		2XN4 4CHB
Enriched GO Terms of Interacting Partners?
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