KLHL2 and BCAM

  • Number of citations of the paper that reports this interaction (PubMedID 25416956)
  • 484
  • Data Source:
  • BioGRID (two hybrid, two hybrid)

KLHL2

BCAM

Description kelch like family member 2 basal cell adhesion molecule (Lutheran blood group)
Image
GO Annotations Cellular Component
Molecular Function
Biological Process
Pathways
Drugs
Diseases
GWAS
  • Alzheimer's disease ( 30636644 24755620)
  • Alzheimer's disease (onset between ages 58 and 79) ( 30979435)
  • Alzheimer's disease in hypertension ( 31055733)
  • Alzheimer's disease in hypertension-negative individuals ( 31055733)
  • Alzheimer's disease or family history of Alzheimer's disease ( 30617256)
  • Alzheimer's disease or HDL levels (pleiotropy) ( 30805717)
  • Blood protein levels ( 30072576 29875488)
  • Body mass index ( 26426971)
  • Body mass index (age>50) ( 26426971)
  • Body mass index x age interaction ( 26426971)
  • Body mass index x sex x age interaction (4df test) ( 26426971)
  • Carotid intima media thickness (maximum) ( 31801372)
  • Carotid intima media thickness (mean) ( 31801372)
  • Cerebrospinal AB1-42 levels in Alzheimer's disease dementia ( 29274321)
  • Cerebrospinal AB1-42 levels in mild cognitive impairment ( 29274321)
  • Cerebrospinal AB1-42 levels in normal cognition ( 29274321)
  • Cerebrospinal fluid AB1-42 levels ( 28247064 29274321)
  • Cerebrospinal fluid p-tau levels ( 29274321)
  • Cerebrospinal fluid p-tau levels in mild cognitive impairment ( 29274321)
  • Cerebrospinal fluid t-tau levels ( 29274321)
  • Cerebrospinal fluid t-tau levels in mild cognitive impairment ( 29274321)
  • Hippocampal volume ( 29274321)
  • Hippocampal volume in Alzheimer's disease dementia ( 29274321)
  • LDL cholesterol ( 30275531)
  • Liver enzyme levels (alkaline phosphatase) ( 33972514)
  • Logical memory (delayed recall) ( 29274321)
  • Logical memory (immediate recall) ( 29274321)
  • Waist-to-hip circumference ratio (smoking years interaction) ( 23192594)
Interacting Genes 32 interacting genes: ACTC1 BCAM BYSL C20orf85 CCDC43 CDC37 CLK2 CUL3 CWC22 ELOA FRAS1 KEAP1 KLHL12 KLHL3 MFAP1 NAP1L2 NTAQ1 PADI6 PIBF1 POLR3C SDCBP TMA16 TNPO2 TRIM50 TXNDC12 UBE2C UBE2D1 UBE2I UCK1 WNK1 WNK4 ZNF114 10 interacting genes: EPB41 KLHL2 KRTAP1-1 KRTAP1-3 LAMA5 MDFI NBPF19 NOTCH2NLA TRIM7 UBE2I
Entrez ID 11275 4059
HPRD ID 09311 00197
Ensembl ID ENSG00000109466 ENSG00000187244
Uniprot IDs B4DFZ5 E9PEX9 O95198 A0A087WXM8 P50895
PDB IDs 2XN4 4CHB 2PET 2PF6
Enriched GO Terms of Interacting Partners?
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