EGLN2 and SPOP

  • Number of citations of the paper that reports this interaction (PubMedID 28089830)
  • 17
  • Data Source:
  • BioGRID (pull down, pull down)

EGLN2

SPOP

Description egl-9 family hypoxia inducible factor 2 speckle type BTB/POZ protein
Image
GO Annotations Cellular Component
Molecular Function
Biological Process
Pathways
Drugs
Diseases
GWAS
  • Alanine aminotransferase levels ( 33547301)
  • Carotid intima media thickness (mean) ( 31801372)
  • Chronic obstructive pulmonary disease ( 22080838)
  • Chronic obstructive pulmonary disease in current smokers ( 33106845)
  • Chronic obstructive pulmonary disease x current smoker interaction (2df) ( 33106845)
  • Hematocrit ( 32888494 27863252)
  • Hemoglobin ( 32888494)
  • Hemoglobin concentration ( 27863252)
  • Hemoglobin levels ( 32327693)
  • Nicotine metabolite ratio in current smokers ( 28921760)
  • Parental longevity (father's attained age) ( 29227965)
  • Post bronchodilator FEV1 ( 26634245)
  • Post bronchodilator FEV1/FVC ratio ( 26634245)
  • Red blood cell count ( 32888494)
  • Serum alkaline phosphatase levels ( 33547301)
  • Smoking behavior ( 20418890)
  • Smoking behaviour (cigarettes smoked per day) ( 30617275)
Interacting Genes 11 interacting genes: A2M CDK2 EPAS1 HIF1A HIF3A MFHAS1 MOB4 PRKCA SPOP SRPK2 TENT5A 68 interacting genes: AEN AMOTL2 AR ARIH1 BRD2 BRD3 BRMS1 CACUL1 CBX4 CCNE1 CDK4 CHAF1A CHD3 CREB5 CTDSPL2 CUL3 DAXX DDIT3 DHX15 DPPA2 EGLN2 ERF ERG FAF1 GATAD2A GCC1 GCC2 GIT2 GLI2 GMEB1 HCST HMGCS1 ILF3 INF2 IRF1 KPNA5 LRCH4 MACROH2A1 MRE11 MYD88 NANOG NCOA3 NUDCD3 PDX1 PIAS1 PIAS3 RANBP9 RBFOX2 RBPJ RPRD2 RTN3 RXRB SETD2 SRRM1 SUMO1 TCOF1 TOPORS TRAF1 TRAF6 UBE2D1 UBE2D2 UBE2E3 UBE2I VPS9D1-AS1 YWHAG ZBTB16 ZCCHC12 ZMYND8
Entrez ID 112398 8405
HPRD ID 06970 16004
Ensembl ID ENSG00000269858 ENSG00000121067
Uniprot IDs A0A024R0R2 Q96KS0 O43791
PDB IDs 5V1B 2CR2 3HQH 3HQI 3HQL 3HQM 3HSV 3HTM 3HU6 3IVB 3IVQ 3IVV 4EOZ 4HS2 4J8Z 4O1V 6F8F 6F8G 6I41 6I5P 6I68 6I7A 7D3D
Enriched GO Terms of Interacting Partners?
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