EGLN2 and EPAS1

  • Number of citations of the paper that reports this interaction (PubMedID 17353276)
  • 38
  • Data Source:
  • BioGRID (pull down, affinity chromatography technology)
  • HPRD (in vitro)

EGLN2

EPAS1

Description egl-9 family hypoxia inducible factor 2 endothelial PAS domain protein 1
Image
GO Annotations Cellular Component
Molecular Function
Biological Process
Pathways
Drugs
Diseases
GWAS
  • Alanine aminotransferase levels ( 33547301)
  • Carotid intima media thickness (mean) ( 31801372)
  • Chronic obstructive pulmonary disease ( 22080838)
  • Chronic obstructive pulmonary disease in current smokers ( 33106845)
  • Chronic obstructive pulmonary disease x current smoker interaction (2df) ( 33106845)
  • Hematocrit ( 32888494 27863252)
  • Hemoglobin ( 32888494)
  • Hemoglobin concentration ( 27863252)
  • Hemoglobin levels ( 32327693)
  • Nicotine metabolite ratio in current smokers ( 28921760)
  • Parental longevity (father's attained age) ( 29227965)
  • Post bronchodilator FEV1 ( 26634245)
  • Post bronchodilator FEV1/FVC ratio ( 26634245)
  • Red blood cell count ( 32888494)
  • Serum alkaline phosphatase levels ( 33547301)
  • Smoking behavior ( 20418890)
  • Smoking behaviour (cigarettes smoked per day) ( 30617275)
Interacting Genes 11 interacting genes: A2M CDK2 EPAS1 HIF1A HIF3A MFHAS1 MOB4 PRKCA SPOP SRPK2 TENT5A 40 interacting genes: APC ARNT ARNT2 ARNTL ARNTL2 BATF BATF2 BATF3 BBS1 BBS2 BBS4 DBP DDIT3 EGLN1 EGLN2 EGLN3 EIF3E EP300 ESR1 ETV4 EWSR1 F12 HSP90AA1 JUN KLHL20 KPNA1 KPNA3 KPNA5 KPNA6 KPNB1 MAX MEF2C NDN PRKD1 SMAD3 SPP1 STAT5A TERF2IP USP20 VHL
Entrez ID 112398 2034
HPRD ID 06970 06787
Ensembl ID ENSG00000269858 ENSG00000116016
Uniprot IDs A0A024R0R2 Q96KS0 B3KW07 Q99814
PDB IDs 5V1B 1P97 2A24 3F1N 3F1O 3F1P 3H7W 3H82 4GHI 4GS9 4PKY 4XT2 5KIZ 5TBM 5UFP 6BVB 6CZW 6D09 6D0B 6D0C 6I7Q 6I7R
Enriched GO Terms of Interacting Partners?
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