NDC80 and MAD1L1

  • Number of citations of the paper that reports this interaction (PubMedID 12351790)
  • 192
  • Data Source:
  • HPRD (in vivo, two hybrid)

NDC80

MAD1L1

Description NDC80 kinetochore complex component mitotic arrest deficient 1 like 1
Image
GO Annotations Cellular Component
Molecular Function
Biological Process
Pathways
Drugs
Diseases
GWAS
  • Metabolite levels ( 23823483)
  • Response to cognitive-behavioural therapy in major depressive disorder ( 31123309)
  • Adult body size ( 32376654)
  • Adverse response to drug ( 30420678)
  • Age at first birth ( 34211149)
  • Age at first sexual intercourse ( 27089180 34211149)
  • Alcohol consumption (drinks per week) ( 30643258)
  • Anorexia nervosa, attention-deficit/hyperactivity disorder, autism spectrum disorder, bipolar disorder, major depression, obsessive-compulsive disorder, schizophrenia, or Tourette syndrome (pleiotropy) ( 31835028)
  • Anthropometric traits (multi-trait analysis) ( 30166351)
  • Anxiety ( 31906708)
  • Autism spectrum disorder or schizophrenia ( 28540026)
  • Bipolar disorder ( 28115744 21926972 27329760)
  • Bitter alcoholic beverage consumption ( 31046077)
  • Cognitive ability, years of educational attainment or schizophrenia (pleiotropy) ( 31374203)
  • Coronary artery disease ( 29212778 33020668)
  • Dimensional psychopathology (Social) ( 29496196)
  • Disruptive behavior disorder and attention deficit hyperactivity disorder ( 33495439)
  • Gastroesophageal reflux disease ( 34187846 31527586)
  • General factor of neuroticism ( 30867560)
  • Gut microbiota relative abundance (Streptococcus) ( 33208821)
  • Hand grip strength ( 29691431)
  • Idiopathic pulmonary fibrosis ( 31710517)
  • Longevity ( 20834067)
  • Mosaic loss of chromosome Y (Y chromosome dosage) ( 28346444 31624269)
  • Myocardial infarction ( 33532862)
  • Number of sexual partners ( 30643258)
  • Platelet count ( 32888494)
  • Plateletcrit ( 32888494)
  • Prostate cancer ( 29892016)
  • Prostate cancer (advanced) ( 29892016)
  • Refractive error ( 32231278)
  • Response to bronchodilator in chronic obstructive pulmonary disease (change in FEV1) ( 26503814)
  • Risk-taking tendency (4-domain principal component model) ( 30643258)
  • Rosacea symptom severity ( 29771307)
  • Schizophrenia ( 28991256 29483656 22688191 30285260 23974872)
  • Schizophrenia or bipolar disorder ( 24280982)
  • Schizophrenia, schizoaffective disorder or bipolar disorder ( 24166486)
  • Sepsis (28-day mortality) ( 32592749)
  • Sleep duration (short sleep) ( 30846698)
  • Smoking initiation ( 33082346)
  • Smoking status (ever vs never smokers) ( 30643258)
  • Superior frontal gyrus volume ( 31530798)
  • Superior temporal gyrus volume ( 31530798)
  • Systolic blood pressure ( 30578418)
  • Testicular germ cell tumor ( 28604728 28604732 23666239)
  • Vaginal microbiome composition (Shannon diversity index) ( 32723796)
Interacting Genes 62 interacting genes: AMOTL2 ATF4 ATP5PO ATP6V1D AURKA AURKB BLOC1S6 CAGE1 CALCOCO1 CCDC136 CCHCR1 CCNH CCNK CENPH CEP63 CKAP5 EPS15L1 EXOC8 FAM9C GOLGA2 HAUS1 HGS HPCA IFT20 INPP1 KIFC3 KLC3 KLHL12 KRT27 KRT6B KRT75 LNX1 MAD1L1 MAD2L1 MFAP1 MIS12 MX1 NDE1 NDEL1 NEK2 NUF2 PFDN1 PPP1R13B PSMC2 RB1 RUFY4 SFR1 SGF29 SKA1 SMC1A SPC25 STX11 TFIP11 THOC7 TOM1L1 TXLNA USHBP1 VPS52 WASHC1 WASHC3 ZNF655 ZWINT 79 interacting genes: AIMP2 ALOX5 AMOTL2 ANXA5 ATG5 BAG5 BIRC2 CAPN7 CCDC57 CCHCR1 CCND2 CDC37 CDK18 CHERP CHST12 COIL CWF19L2 FAM131C FAM90A1 FSCN1 FXR1 GAS8 GPKOW HAUS1 HDAC1 HDAC2 HOXA10 KIF9 LENG1 LGALSL LMO1 LMO3 LNX1 MAD2L1 MAX MFAP1 MLX NDC80 NEBL NEK2 NINL NONO NTAQ1 NXPH1 PIBF1 PIN4 PML PPP1R18 PRKAR1B PSMA1 RNF8 RPA3 S100P SIN3A SIN3B SPATA18 SPATA2 STAM SUPT5H SYT17 SYT6 TCAF1 TEX11 TEX33 TPM1 TPM3 TPR TRIM29 TSC22D3 TSGA10 TSHZ3 TTYH3 TUBGCP4 TULP4 UBC UBTF USP15 YJU2 ZSCAN32
Entrez ID 10403 8379
HPRD ID 06277 04065
Ensembl ID ENSG00000080986 ENSG00000002822
Uniprot IDs A8K031 O14777 Q9Y6D9
PDB IDs 2IGP 2VE7 3IZ0 1GO4 4DZO
Enriched GO Terms of Interacting Partners?
Tagcloud ?
Tagcloud (Difference) ?
Tagcloud (Intersection) ?