MAD1L1 and CDC37

  • Number of citations of the paper that reports this interaction (PubMedID 32296183)
  • 86
  • Data Source:
  • BioGRID (two hybrid)

MAD1L1

CDC37

Description mitotic arrest deficient 1 like 1 cell division cycle 37, HSP90 cochaperone
Image
GO Annotations Cellular Component
Molecular Function
Biological Process
Pathways
Drugs
Diseases
GWAS
  • Adult body size ( 32376654)
  • Adverse response to drug ( 30420678)
  • Age at first birth ( 34211149)
  • Age at first sexual intercourse ( 27089180 34211149)
  • Alcohol consumption (drinks per week) ( 30643258)
  • Anorexia nervosa, attention-deficit/hyperactivity disorder, autism spectrum disorder, bipolar disorder, major depression, obsessive-compulsive disorder, schizophrenia, or Tourette syndrome (pleiotropy) ( 31835028)
  • Anthropometric traits (multi-trait analysis) ( 30166351)
  • Anxiety ( 31906708)
  • Autism spectrum disorder or schizophrenia ( 28540026)
  • Bipolar disorder ( 28115744 21926972 27329760)
  • Bitter alcoholic beverage consumption ( 31046077)
  • Cognitive ability, years of educational attainment or schizophrenia (pleiotropy) ( 31374203)
  • Coronary artery disease ( 29212778 33020668)
  • Dimensional psychopathology (Social) ( 29496196)
  • Disruptive behavior disorder and attention deficit hyperactivity disorder ( 33495439)
  • Gastroesophageal reflux disease ( 34187846 31527586)
  • General factor of neuroticism ( 30867560)
  • Gut microbiota relative abundance (Streptococcus) ( 33208821)
  • Hand grip strength ( 29691431)
  • Idiopathic pulmonary fibrosis ( 31710517)
  • Longevity ( 20834067)
  • Mosaic loss of chromosome Y (Y chromosome dosage) ( 28346444 31624269)
  • Myocardial infarction ( 33532862)
  • Number of sexual partners ( 30643258)
  • Platelet count ( 32888494)
  • Plateletcrit ( 32888494)
  • Prostate cancer ( 29892016)
  • Prostate cancer (advanced) ( 29892016)
  • Refractive error ( 32231278)
  • Response to bronchodilator in chronic obstructive pulmonary disease (change in FEV1) ( 26503814)
  • Risk-taking tendency (4-domain principal component model) ( 30643258)
  • Rosacea symptom severity ( 29771307)
  • Schizophrenia ( 28991256 29483656 22688191 30285260 23974872)
  • Schizophrenia or bipolar disorder ( 24280982)
  • Schizophrenia, schizoaffective disorder or bipolar disorder ( 24166486)
  • Sepsis (28-day mortality) ( 32592749)
  • Sleep duration (short sleep) ( 30846698)
  • Smoking initiation ( 33082346)
  • Smoking status (ever vs never smokers) ( 30643258)
  • Superior frontal gyrus volume ( 31530798)
  • Superior temporal gyrus volume ( 31530798)
  • Systolic blood pressure ( 30578418)
  • Testicular germ cell tumor ( 28604728 28604732 23666239)
  • Vaginal microbiome composition (Shannon diversity index) ( 32723796)
Interacting Genes 79 interacting genes: AIMP2 ALOX5 AMOTL2 ANXA5 ATG5 BAG5 BIRC2 CAPN7 CCDC57 CCHCR1 CCND2 CDC37 CDK18 CHERP CHST12 COIL CWF19L2 FAM131C FAM90A1 FSCN1 FXR1 GAS8 GPKOW HAUS1 HDAC1 HDAC2 HOXA10 KIF9 LENG1 LGALSL LMO1 LMO3 LNX1 MAD2L1 MAX MFAP1 MLX NDC80 NEBL NEK2 NINL NONO NTAQ1 NXPH1 PIBF1 PIN4 PML PPP1R18 PRKAR1B PSMA1 RNF8 RPA3 S100P SIN3A SIN3B SPATA18 SPATA2 STAM SUPT5H SYT17 SYT6 TCAF1 TEX11 TEX33 TPM1 TPM3 TPR TRIM29 TSC22D3 TSGA10 TSHZ3 TTYH3 TUBGCP4 TULP4 UBC UBTF USP15 YJU2 ZSCAN32 179 interacting genes: A2M ACTB ACTG1 AKT1 AMOTL2 APOE APP AR BEND7 BHLHB9 BLZF1 BTBD10 BTBD3 C19orf44 CAMK2A CAMK2B CAMK2G CARD10 CARD9 CAVIN1 CBY2 CC2D1A CCDC138 CCDC152 CCDC91 CCHCR1 CDC37L1 CDK2 CDK3 CDK4 CDK5 CDK6 CDK7 CEP55 CEP70 CGGBP1 CHGA CHUK CKS1B CKS2 CRYM CSNK2A1 CSNK2A2 CT45A1 CTAG1A CTAG1B CUTC CYP2C9 DCTN1 DEAF1 DISC1 ECSIT EIF2AK1 EIF2S1 ELAVL3 ENOX2 EXOSC1 FAM118A FAM9B FATE1 FBXL12 FBXW4 GAS7 GAS8 GCDH GCH1 GFAP GMCL1 GOLGA2 GOLGA6L9 GRAMD2B GRIPAP1 HIVEP1 HOMER3 HSF2BP HSP90AA1 IFIT5 IKBKB IKBKE IKBKG IKZF3 IMMT JRK KATNBL1 KCTD13 KCTD9 KIFC3 KLHL2 KRT75 KRT76 LMNB2 LONP1 LOXL4 LUC7L2 LZTS1 MAD1L1 MAP3K14 MAP3K3 MDFI MID1 MIPOL1 MRPL9 MTOR MZT2B NCOA5 NECAB1 NECAB2 NOS3 NR2C2 NRIP3 NT5C1A OGA OGT PAICS PDE9A PIBF1 PNMA2 POU6F2 PPHLN1 PPP5C PRAM1 PRDX2 PRKAR1B PRMT1 PRMT5 PRPH PRR20A PRR20B PRR20C PRR20D PRR20E PSMC6 PSME1 PTGES3 RABGEF1 RAD23A RAF1 REEP6 RNF32 ROPN1 RPS15A SAFB SEPTIN3 SNX5 SPTBN4 SQSTM1 SRC SRRM4 SSNA1 STAMBPL1 STIP1 STK11 STK32A STX1A SYCE2 SYCP3 TBK1 TCF4 THAP1 THAP7 TNFAIP1 TNIP1 TRAF2 TRAF3 TRAF5 TRIM54 UBE2I USHBP1 WAC ZBED1 ZBTB26 ZBTB8A ZNF205 ZNF235 ZNF266 ZNF276 ZNF655 ZNF667 ZNF837
Entrez ID 8379 11140
HPRD ID 04065 05456
Ensembl ID ENSG00000002822 ENSG00000105401
Uniprot IDs Q9Y6D9 A0A024R7B7 Q16543
PDB IDs 1GO4 4DZO 1US7 2K5B 2N5X 2NCA 2W0G 5FWK 5FWL 5FWM 5FWP 5HPE
Enriched GO Terms of Interacting Partners?
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